Repository at Hanyang UniversityCOLLEGE OF ENGINEERING SCIENCES[E](공학대학)MATERIALS SCIENCE AND CHEMICAL ENGINEERING(재료화학공학과)Articles
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Effect of alpha-resorcylic acid-L-phenylalanine amide on collagen synthesis and matrix metalloproteinase expression in fibroblasts
- Title
- Effect of alpha-resorcylic acid-L-phenylalanine amide on collagen synthesis and matrix metalloproteinase expression in fibroblasts
- Author
- 김종호
- Keywords
- Resorcylic acid derivative; Collagen synthesis; Suppression of MMPs expression
- Issue Date
- 2014-02
- Publisher
- Pergamon Press Ltd.
- Citation
- Bioorganic and Medicinal Chemistry Letters, v. 24, NO. 3, Page. 742-745
- Abstract
- Regulation of collagen synthesis and matrix metalloproteinases (MMPs) expression levels has been an important issue in medicinal, pharmaceutical and cosmetic industries. Herein, alpha-Resorcylic acid-phenylalanine amide (alpha-RA-F) was prepared and its biological activities were observed. We found that alpha-RA-F boosted collagen synthesis and reduced MMPs expression levels in human fibroblasts without cytotoxicity. (C) 2014 Elsevier Ltd. All rights reserved.
- URI
- https://www.sciencedirect.com/science/article/pii/S0960894X13014947?via%3Dihubhttps://repository.hanyang.ac.kr/handle/20.500.11754/175973
- ISSN
- 0960-894X;1464-3405
- Appears in Collections:
- COLLEGE OF ENGINEERING SCIENCES[E](공학대학) > MATERIALS SCIENCE AND CHEMICAL ENGINEERING(재료화학공학과) > Articles
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