Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김봉영 | - |
dc.date.accessioned | 2022-08-29T07:14:04Z | - |
dc.date.available | 2022-08-29T07:14:04Z | - |
dc.date.issued | 2020-11 | - |
dc.identifier.citation | JOURNAL OF KOREAN MEDICAL SCIENCE, v. 35, no. 47, article no. e407 | en_US |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.issn | 1598-6357 | - |
dc.identifier.uri | https://jkms.org/DOIx.php?id=10.3346/jkms.2020.35.e407 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/172607 | - |
dc.description.abstract | Previous exposure to antimicrobials is a major risk factor for Clostridioides difficile infection (CDI). Antibiotic prescription and C. difficile toxin assay records of patients admitted to a tertiary hospital in Korea from 2009 to 2013 were collected to investigate the association between antibiotic consumption and CDI incidence. A Spearman's correlation analysis between CDI incidence (positive result of toxin assay/10,000 admissions) and antibiotic consumption (defined daily dose/1,000 patient-days) was performed on a monthly basis. Using the matched month approach, we found a significant correlation between CDI rate and moxifloxacin consumption (Spearman's r = 0.351, P ˂ 0.001). Furthermore, using the onemonth delay approach, we found that the consumption of clindamycin (Spearman's r = 0.272, P = 0.037) and moxifloxacin (Spearman's r = 0.297, P = 0.022) was significantly correlated with CDI incidence. Extended-spectrum cephalosporins did not have any effect on CDI incidence. | en_US |
dc.description.sponsorship | This work was supported by the research fund of BCWorld Pharm. Co., Ltd. (2019). | en_US |
dc.language.iso | en | en_US |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | en_US |
dc.subject | Clostridioides difficile | en_US |
dc.subject | Antibiotics | en_US |
dc.subject | Correlation | en_US |
dc.subject | Stewardship | en_US |
dc.subject | Korea | en_US |
dc.title | Association between Antibiotic Consumption and Incidence of Clostridioides difficile Infection in a Hospital | en_US |
dc.type | Article | en_US |
dc.relation.no | 47 | - |
dc.relation.volume | 35 | - |
dc.identifier.doi | 10.3346/jkms.2020.35.e407 | - |
dc.relation.page | 407-407 | - |
dc.relation.journal | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.contributor.googleauthor | Kim, Bongyoung | - |
dc.contributor.googleauthor | Kim, Jieun | - |
dc.contributor.googleauthor | Pai, Hyunjoo | - |
dc.relation.code | 2020046958 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | sobakas | - |
dc.identifier.researcherID | H-3409-2018 | - |
dc.identifier.orcid | https://orcid.org/0000-0002-5029-6597 | - |
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