Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김기현 | - |
dc.date.accessioned | 2021-04-09T05:39:10Z | - |
dc.date.available | 2021-04-09T05:39:10Z | - |
dc.date.issued | 2020-02 | - |
dc.identifier.citation | CHEMICAL ENGINEERING JOURNAL, v. 382, article no. 123002 | en_US |
dc.identifier.issn | 1385-8947 | - |
dc.identifier.issn | 1873-3212 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S138589471932412X?via%3Dihub | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/161310 | - |
dc.description.abstract | Diclofenac (DCF) is one of the most widely used anti-inflammatory drugs worldwide to be ubiquitously present in various environmental compartments. The occurrence and concentration of DCF in water bodies are emerging issues due to its detrimental effects and chronic toxicity in various organisms. In an effort to develop or improve quantitation techniques for DCF in diverse environmental media, the use of porous molecularly imprinted polymers (PMIP) as extractive adsorbents has been drawing great attention in recent years. In this study, PMIP was synthesized as media for solid-phase extraction (SPE) of DCF for analysis by high performance liquid chromatography. The limits of detection and quantification for DCF were in 12-20 and 39-66 pg/mL, respectively, with a linearity over 0.1-100 ng/mL (R-2 ˃ 0.99). This method offered high recovery for aqueous (i.e., 95.41-124.14%) and pharmaceutical compounds (i.e., 93.91-96.48%) with relative standard deviation less than 2%. In addition, the cross-reactivity and sensitivity of this PMIP-SPE-HPLC method when tested against the conventional C18-based SPE method confirmed that it should be highly effective for the quantitation of DCF in aqueous pharmaceutical compounds. | en_US |
dc.description.sponsorship | The authors are grateful to UGC, New Delhi for providing financial support under scheme MRP-MAJOR-CHEM-2013-36417. KHK acknowledges the support of the R&D Center for Green Patrol Technologies through the R&D for Global Top Environmental Technologies funded by the Ministry of Environment (Grant No: 2018001850001) as well as a grant from the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, & Future Planning (Grant No: 2016R1E1A1A01940995). | en_US |
dc.language.iso | en | en_US |
dc.publisher | ELSEVIER SCIENCE SA | en_US |
dc.subject | Porous molecularly imprinted polymer | en_US |
dc.subject | Diclofenac | en_US |
dc.subject | Aqueous samples | en_US |
dc.subject | Pharmaceutical formulations | en_US |
dc.title | Porous molecularly-imprinted polymer for detecting diclofenac in aqueous pharmaceutical compounds | en_US |
dc.type | Article | en_US |
dc.relation.volume | 382 | - |
dc.identifier.doi | 10.1016/j.cej.2019.123002 | - |
dc.relation.page | 1-11 | - |
dc.relation.journal | CHEMICAL ENGINEERING JOURNAL | - |
dc.contributor.googleauthor | Mohiuddin, Irshad | - |
dc.contributor.googleauthor | Grover, Aman | - |
dc.contributor.googleauthor | Aulakh, Jatinder Singh | - |
dc.contributor.googleauthor | Lee, Sang-Soo | - |
dc.contributor.googleauthor | Malik, Ashok Kumar | - |
dc.contributor.googleauthor | Kim, Ki-Hyun | - |
dc.relation.code | 2020052975 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF CIVIL AND ENVIRONMENTAL ENGINEERING | - |
dc.identifier.pid | kkim61 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.