Magnetic resonance image-based tomotherapy planning for prostate cancer
- Title
- Magnetic resonance image-based tomotherapy planning for prostate cancer
- Author
- 정윤선
- Keywords
- Prostatic neoplasms; Magnetic resonance imaging; Helical tomotherapy
- Issue Date
- 2019-12
- Publisher
- Korean Society for Therapeutic Radiology and Oncology
- Citation
- Radiation Oncology Journal, v. 38, no. 1, page. 52-59
- Abstract
- Purpose: To evaluate and compare the feasibilities of magnetic resonance (MR) image-based planning using synthetic computed tomography (sCT) versus CT (pCT)-based planning in helical tomotherapy for prostate cancer.
Materials and Methods: A retrospective evaluation was performed in 16 patients with prostate cancer who had been treated with helical tomotherapy. MR images were acquired using a dedicated therapy sequence; sCT images were generated using magnetic resonance for calculating attenuation (MRCAT). The three-dimensional dose distribution according to sCT was recalculated using a previously optimized plan and was compared with the doses calculated using pCT.
Results: The mean planning target volume doses calculated by sCT and pCT differed by 0.65% +/- 1.11% (p = 0.03). Three-dimensional gamma analysis at a 2%/2 mm dose difference/distance to agreement yielded a pass rate of 0.976 (range, 0.658 to 0.986).
Conclusion: The dose distribution results obtained using tomotherapy from MR-only simulations were in good agreement with the dose distribution results from simulation CT, with mean dose differences of less than 1% for target volume and normal organs in patients with prostate cancer.
- URI
- https://www.e-roj.org/journal/view.php?doi=10.3857/roj.2020.00101https://repository.hanyang.ac.kr/handle/20.500.11754/155894
- ISSN
- 2234-3156
- DOI
- 10.3857/roj.2020.00101
- Appears in Collections:
- COLLEGE OF ENGINEERING[S](공과대학) > NUCLEAR ENGINEERING(원자력공학과) > Articles
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