Clinical characteristics of patients with leiomyoma who undergo surgery after high intensity focused ultrasound (HIFU)
- Title
- Clinical characteristics of patients with leiomyoma who undergo surgery after high intensity focused ultrasound (HIFU)
- Author
- 최중섭
- Keywords
- Leiomyoma; High-intensity focused ultrasound ablation; Myomectomy; Hysterectomy
- Issue Date
- 2019-07
- Publisher
- 대한산부인과학회
- Citation
- Obstetrics & Gynecology Science, v. 62, no. 4, Page. 258-263
- Abstract
- Objective
We evaluated the clinical characteristics of patients who underwent surgery after high intensity focused ultrasound
(HIFU) to treat uterine leiomyoma.
Methods
From June 2016 to September 2017, patients at our hospital who underwent HIFU to treat uterine leiomyoma prior
to surgery were enrolled. All patients underwent pelvic magnetic resonance imaging (MRI) before and after HIFU. If
6 months had passed since the last pelvic MRI was performed, imaging was performed again before the operation.
Results
A total of 12 patients were analyzed. The median age was 45 (range, 28–51) years. The median body mass index was
24.9 (range, 18.1–29.2) kg/m2. The median size of the leiomyoma was 10.1 (range, 7.8–14.0) cm before HIFU, which
changed to 8.75 (range, 5.9–14.8) cm after HIFU. The median size increased to 9.1 (range, 5.9–18.0) cm before the
operation. Surgery was planned for several reasons, including an increase in the leiomyoma size (n=6), persistent
symptoms (n=4), and newly developed lesion (n=2). The median interval between HIFU and surgery was 7 (range,
3–32) months. Ten of the 12 patients underwent laparoscopic surgery, while the others underwent laparotomy;
6 patients also underwent laparoscopic myomectomy, and 4 underwent hysterectomy. Histopathologic findings
showed infarction-type necrosis surrounded by granulation tissue with the infiltration of lymphocytes and
macrophages in all patients.
Conclusion
Treatment of leiomyoma with operative procedures should be considered in selected patients with tumor size greater
than 10 cm, multiple tumors, and persistent symptoms after HIFU treatment.
- URI
- https://www.ogscience.org/journal/view.php?doi=10.5468/ogs.2019.62.4.258https://repository.hanyang.ac.kr/handle/20.500.11754/152175
- ISSN
- 2287-8572; 2287-8580
- DOI
- 10.5468/ogs.2019.62.4.258
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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