Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김기현 | - |
dc.date.accessioned | 2019-12-10T20:31:54Z | - |
dc.date.available | 2019-12-10T20:31:54Z | - |
dc.date.issued | 2018-12 | - |
dc.identifier.citation | APPLIED SCIENCES-BASEL, v. 8, no. 12, Article no. 2699 | en_US |
dc.identifier.issn | 2076-3417 | - |
dc.identifier.uri | https://www.mdpi.com/2076-3417/8/12/2699 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/121178 | - |
dc.description.abstract | An experimental method was developed and validated for the collection and analysis of tobacco-specific nitrosamines (TSNAs) that are present in electronic cigarette (EC) liquid or are released from aerosol samples using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) system. As part of this study, the relative recovery of four target TSNAs was assessed by spiking standards in a mixture of propylene glycol and vegetable glycerin. Recovery was assessed against two major variables: (1) the chemical media (solution) selected for sample dilution (acetonitrile [ACN] vs. ammonium acetate [AA]) and (2) the type of sampling filter used (Cambridge filter pad [CFP] vs. quartz wool [QW] tube). The average recovery of TSNAs in terms of variable 1 was 134 +/- 22.1% for ACN and 92.6 +/- 8.27% for AA. The average recovery in terms of variable 2 was 83.4 +/- 7.33% for QW and 58.5 +/- 12.9% for CFP. Based on these conditions, the detection limits of N'-nitrosonornicotine (NNN), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), N'-nitrosoanatabine (NAT), and N'-nitrosoanabasine (NAB) were calculated as 4.40, 4.47, 3.71, and 3.28 ng mL(-1), respectively. The concentration of TSNAs in liquid and aerosol samples of six commercial EC solutions was measured as below the detection limit. | en_US |
dc.description.sponsorship | This study was supported by a grant from the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, & Future Planning (No. 2016R1E1A1A01940995). This research was supported by a grant (14182MFDS977) from the Ministry of Food and Drug Safety in 2017. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | MDPI | en_US |
dc.subject | tobacco specific-nitrosamines | en_US |
dc.subject | electronic cigarette | en_US |
dc.subject | liquid chromatography-tandem mass spectrometry | en_US |
dc.title | Analytical Method for Measurement of Tobacco-Specific Nitrosamines in E-Cigarette Liquid and Aerosol | en_US |
dc.type | Article | en_US |
dc.relation.no | 12 | - |
dc.relation.volume | 8 | - |
dc.identifier.doi | 10.3390/app8122699 | - |
dc.relation.page | 1-1 | - |
dc.relation.journal | APPLIED SCIENCES-BASEL | - |
dc.contributor.googleauthor | Lee, Yoon-Seo | - |
dc.contributor.googleauthor | Kim, Ki-Hyun | - |
dc.contributor.googleauthor | Lee, Sang Soo | - |
dc.contributor.googleauthor | Brown, Richard J. C. | - |
dc.contributor.googleauthor | Jo, Sang-Hee | - |
dc.relation.code | 2018009765 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF CIVIL AND ENVIRONMENTAL ENGINEERING | - |
dc.identifier.pid | kkim61 | - |
dc.identifier.researcherID | I-8499-2018 | - |
dc.identifier.orcid | https://orid.org/0000-0003-0487-4242 | - |
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