Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 전대원 | - |
dc.date.accessioned | 2019-12-10T20:18:20Z | - |
dc.date.available | 2019-12-10T20:18:20Z | - |
dc.date.issued | 2018-12 | - |
dc.identifier.citation | HEPATOLOGY RESEARCH, v. 48, no. 3, page. E22-E29 | en_US |
dc.identifier.issn | 1386-6346 | - |
dc.identifier.issn | 1872-034X | - |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/full/10.1111/hepr.12918 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/121158 | - |
dc.description.abstract | Aim: Composition of macronutrients is important in non-alcoholic fatty liver disease (NAFLD). Diet education programs that mainly emphasize reducing fat consumption have been used for NAFLD patients. We compared the efficacy of conventional low-fat diet education with low-carbohydrate diet education in Korean NAFLD patients.Methods: One hundred and six NAFLD patients were randomly allocated to low-fat diet education or low-carbohydrate education groups for 8weeks. Liver chemistry, liver/spleen ratio, and visceral fat using abdominal tomography were measured.Results: Intrahepatic fat accumulation decreased significantly in the low-carbohydrate group compared to low-fat group (liver/spleen 0.85 vs. 0.92, P<0.05). Normalization of ALT activity at week 8 was 38.5% for the low-carbohydrate and 16.7% for the low-fat group (P=0.016). Not only liver enzyme, but also low density lipoprotein cholesterol and blood pressure levels significantly decreased in the low-carbohydrate group. Total energy intake was also further decreased in the low-carbohydrate group compared to the low-fat group. Although body weight changes were not different between the two groups, the carbohydrate group had a lower total abdominal fat amount.Conclusions: A low-carbohydrate diet program is more realistic and effective in reducing total energy intake and hepatic fat content in Korean NAFLD patients. | en_US |
dc.description.sponsorship | This work was supported by a grant (12162MFDS159) from the Ministry of Food and Drug Safety in 2012 and Soonchunhyang University Research Fund. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | WILEY | en_US |
dc.subject | carbohydrate | en_US |
dc.subject | fat | en_US |
dc.subject | non-alcoholic fatty liver disease | en_US |
dc.title | Comparison of efficacy of low-carbohydrate and low-fat diet education programs in non-alcoholic fatty liver disease: A randomized controlled study | en_US |
dc.type | Article | en_US |
dc.relation.no | 3 | - |
dc.relation.volume | 48 | - |
dc.identifier.doi | 10.1111/hepr.12918 | - |
dc.relation.page | 22-29 | - |
dc.relation.journal | HEPATOLOGY RESEARCH | - |
dc.contributor.googleauthor | Jang, Eun Chul | - |
dc.contributor.googleauthor | Jun, Dae Won | - |
dc.contributor.googleauthor | Lee, Seung Min | - |
dc.contributor.googleauthor | Cho, Yong kyun | - |
dc.contributor.googleauthor | Ahn, Sang Bong | - |
dc.relation.code | 2018007310 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | noshin | - |
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