Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박성열 | - |
dc.date.accessioned | 2019-12-10T02:00:59Z | - |
dc.date.available | 2019-12-10T02:00:59Z | - |
dc.date.issued | 2018-11 | - |
dc.identifier.citation | MEDICINE, v. 97, no. 45, Article no. e13102 | en_US |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.issn | 1536-5964 | - |
dc.identifier.uri | https://insights.ovid.com/crossref?an=00005792-201811090-00044 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/120614 | - |
dc.description.abstract | Background: Robot-assisted partial nephrectomy (RPN) and focal therapy (FT) have both been successfully employed in the management of small renal masses. However, despite this being the era of minimally invasive surgery, few comparative studies exist on RPN and FT. The aim of our study is to review perioperative, renal functional and oncologic outcomes of FT and RPN in cT1 renal masses.Methods: Literature published in Medline, EMBASE, and Cochrane Library databases up to April 22, 2018, was systematically searched. We included literature comparing outcomes of FT (radiofrequency ablation, cryoablation, microwave ablation, and irreversible electroporation) and RPN. Studies that reported only on laparoscopic partial nephrectomy or open partial nephrectomy, and review articles, editorials, letters, or cost analyses were excluded. In total, data from 1166 patients were included.Results: From 858 total articles, 7 nonrandomized, observational studies were included. Compared with RPN, FT was associated with a significantly lower decrease of estimated glomerular filtration rate (weighted mean difference [WMD] -8.06mL/min/1.73m(2); confidence interval [CI]-15.85 to-0.26; P=.04), and lower estimated blood loss (WMD -49.61mL; CI-60.78 to -38.45; P<.001). However, patients who underwent FT had a significantly increased risk of local recurrence (risk ratio [RR] 9.89; CI 4.24-23.04; P<.001) and distant metastasis (RR 6.42; CI 1.70-24.33; P=.006). However, operative times, lengths of stay, and complication rates were revealed to be similar between FT and RPN.Conclusion: RPN has a substantial advantage in preventing cancer recurrence. However, in the era of minimally invasive surgery, FT has advantages in renal function preservation and less bleeding. Long-term follow-up for survival rates and comparative analysis of microwave ablation and irreversible electroporation are needed to extend FT for patients with significant morbidities and for those who need sufficient renal function preservation with minimal bleeding. | en_US |
dc.description.sponsorship | This research was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (NRF-2017R1C1B5018097). This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Education (NRF-2018R1D1A1B07051225). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | en_US |
dc.subject | ablation techniques | en_US |
dc.subject | kidney | en_US |
dc.subject | meta-analysis | en_US |
dc.subject | nephrectomy | en_US |
dc.subject | robotics | en_US |
dc.title | Focal therapy versus robot-assisted partial nephrectomy in the management of clinical T1 renal masses A systematic review and meta-analysis | en_US |
dc.type | Article | en_US |
dc.relation.no | 45 | - |
dc.relation.volume | 97 | - |
dc.identifier.doi | 10.1097/MD.0000000000013102 | - |
dc.relation.page | 1-9 | - |
dc.relation.journal | MEDICINE | - |
dc.contributor.googleauthor | Yoon, Young Eun | - |
dc.contributor.googleauthor | Lee, Hyung Ho | - |
dc.contributor.googleauthor | Kim, Ki Hong | - |
dc.contributor.googleauthor | Park, Sung Yul | - |
dc.contributor.googleauthor | Moon, Hong Sang | - |
dc.contributor.googleauthor | Lee, Seung Ryeol | - |
dc.contributor.googleauthor | Hong, Young Kwon | - |
dc.contributor.googleauthor | Park, Dong Soo | - |
dc.contributor.googleauthor | Kim, Dae Keun | - |
dc.relation.code | 2018002227 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | syparkuro | - |
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