Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김기현 | - |
dc.date.accessioned | 2019-12-08T18:01:05Z | - |
dc.date.available | 2019-12-08T18:01:05Z | - |
dc.date.issued | 2018-07 | - |
dc.identifier.citation | TOXICOLOGY RESEARCH, v. 7, no. 5, page. 931-941 | en_US |
dc.identifier.issn | 2045-452X | - |
dc.identifier.issn | 2045-4538 | - |
dc.identifier.uri | https://pubs.rsc.org/en/content/articlelanding/2018/TX/C8TX00087E#!divAbstract | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/119539 | - |
dc.description.abstract | More effective antibiotics are needed to overcome the problem of multidrug resistance. The antibacterial efficacies of three Zn-based nano metal-organic frameworks (nMOFs) - IRMOF-3, MOF-5, and Zn-BTC - were explored, both alone and as mixtures with ampicillin and kanamycin. When tested against Escherichia coli, Staphylococcus aureus, Staphylococcus lentus, and Listeria monocytogenes, the nMOF/drug mixtures demonstrated synergistic (IRMOF-3/kanamycin) or additive (other nMOF/drug combinations) effects compared with the nMOFs or antibiotics alone. Zn-Based nMOFs can reduce the burden of the new discovery of antimicrobial pharmaceuticals by increasing the potency of existing antibiotics. | en_US |
dc.description.sponsorship | The research was funded by the DBT (Department of Biotechnology), India project (No. BT/PR18868/BCE/8/1370/2016). S. K. P, S. K. B. and J. M. thank DST, CSIR-SRF and UGC, New Delhi, India, respectively for their research fellowships. The authors thank the Director of CSIR-CSIO, Chandigarh, India, for providing infrastructural facilities. K. H. K. acknowledges the support from grants from the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, & Future Planning (No. 2016R1E1A1A01940995). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | ROYAL SOC CHEMISTRY | en_US |
dc.subject | KLEBSIELLA-PNEUMONIAE | en_US |
dc.subject | MULTIDRUG-RESISTANCE | en_US |
dc.subject | DRUG-DELIVERY | en_US |
dc.subject | ANTIBIOTIC-RESISTANCE | en_US |
dc.subject | HUMAN-DISEASE | en_US |
dc.subject | IN-VITRO | en_US |
dc.subject | NANOPARTICLES | en_US |
dc.subject | CYTOTOXICITY | en_US |
dc.subject | ZINC | en_US |
dc.subject | STRATEGIES | en_US |
dc.title | Bioactive nano-metal-organic frameworks as antimicrobials against Gram-positive and Gram-negative bacteria | en_US |
dc.type | Article | en_US |
dc.relation.no | 5 | - |
dc.relation.volume | 7 | - |
dc.identifier.doi | 10.1039/c8tx00087e | - |
dc.relation.page | 931-941 | - |
dc.relation.journal | TOXICOLOGY RESEARCH | - |
dc.contributor.googleauthor | Bhardwaj, Neha | - |
dc.contributor.googleauthor | Pandey, Satish K. | - |
dc.contributor.googleauthor | Mehta, Jyotsana | - |
dc.contributor.googleauthor | Bhardwaj, Sanjeev K. | - |
dc.contributor.googleauthor | Kim, Ki-Hyun | - |
dc.contributor.googleauthor | Deep, Akash | - |
dc.relation.code | 2018009322 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF CIVIL AND ENVIRONMENTAL ENGINEERING | - |
dc.identifier.pid | kkim61 | - |
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