Emission and Cytotoxicity of Surgical Smoke: Cholesta-3,5-Diene Released from Pyrolysis of Prostate Tissue
- Title
- Emission and Cytotoxicity of Surgical Smoke: Cholesta-3,5-Diene Released from Pyrolysis of Prostate Tissue
- Author
- 김기현
- Keywords
- surgical aerosol; surgical carbonaceous material; toxicity; surgical smoke
- Issue Date
- 2018-07
- Publisher
- MDPI
- Citation
- ATMOSPHERE, v. 9, no. 10, Article no. 381
- Abstract
- Respiratory and lung irritants can be a by-product of the surgical pyrolysis of human tissues. Seven prostate tissues were collected during the transurethral resection of a prostate (TURP). Tissue samples, pyrolyzed in a pyrolysis sampling system, were collected and analyzed for the characterization of aerosols in the surgical smoke. In the pyrolyzed particulate matter (PM) from the TURP, Cholestra-3,5-diene was identified as the most dominant component along with 9-methylanthracene, hentriacontane, and dotriacontane based on the mass fragment structure determined using gas chromatography-mass spectrometry (GC-MS). As a molecular marker, Cholesta-3,5-diene can be associated with a cytotoxic in primary human oral keratinocytes (HOK). In this research, the presence of Cholestra-3,5-diene is reported for the first time as a by-product of surgical pyrolysis.
- URI
- https://www.mdpi.com/2073-4433/9/10/381https://repository.hanyang.ac.kr/handle/20.500.11754/119349
- ISSN
- 2073-4433
- DOI
- 10.3390/atmos9100381
- Appears in Collections:
- COLLEGE OF ENGINEERING[S](공과대학) > CIVIL AND ENVIRONMENTAL ENGINEERING(건설환경공학과) > Articles
- Files in This Item:
- Emission and Cytotoxicity of Surgical Smoke Cholesta-3,5-Diene Released from Pyrolysis of Prostate Tissue.pdfDownload
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