Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤영은 | - |
dc.date.accessioned | 2019-12-04T01:43:32Z | - |
dc.date.available | 2019-12-04T01:43:32Z | - |
dc.date.issued | 2018-01 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF UROLOGY, v. 25, no. 7, page. 690-697 | en_US |
dc.identifier.issn | 0919-8172 | - |
dc.identifier.issn | 1442-2042 | - |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/abs/10.1111/iju.13705 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/117016 | - |
dc.description.abstract | ObjectivesTo develop a predictive nomogram for chronic kidney disease-free survival probability in the long term after partial nephrectomy.MethodsA retrospective analysis was carried out of 698 patients with T1 renal tumors undergoing partial nephrectomy at a tertiary academic institution. A multivariable Cox regression analysis was carried out based on parameters proven to have an impact on postoperative renal function. Patients with incomplete data, <12 months follow up and preoperative chronic kidney disease stage III or greater were excluded. The study end-points were to identify independent risk factors for new-onset chronic kidney disease development, as well as to construct a predictive model for chronic kidney disease-free survival probability after partial nephrectomy.ResultsThe median age was 52 years, median tumor size was 2.5 cm and mean warm ischemia time was 28 min. A total of 91 patients (13.1%) developed new-onset chronic kidney disease at a median follow up of 60 months. The chronic kidney disease-free survival rates at 1, 3, 5 and 10 year were 97.1%, 94.4%, 85.3% and 70.6%, respectively. On multivariable Cox regression analysis, age (1.041, P = 0.001), male sex (hazard ratio 1.653, P < 0.001), diabetes mellitus (hazard ratio 1.921, P = 0.046), tumor size (hazard ratio 1.331, P < 0.001) and preoperative estimated glomerular filtration rate (hazard ratio 0.937, P < 0.001) were independent predictors for new-onset chronic kidney disease. The C-index for chronic kidney disease-free survival was 0.853 (95% confidence interval 0.815-0.895).ConclusionWe developed a novel nomogram for predicting the 5-year chronic kidney disease-free survival probability after on-clamp partial nephrectomy. This model might have an important role in partial nephrectomy decision-making and follow-up plan after surgery. External validation of our nomogram in a larger cohort of patients should be considered. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | WILEY | en_US |
dc.subject | chronic kidney disease | en_US |
dc.subject | nomogram | en_US |
dc.subject | on-clamp | en_US |
dc.subject | partial nephrectomy | en_US |
dc.subject | renal function | en_US |
dc.title | Yonsei nomogram: A predictive model of new-onset chronic kidney disease after on-clamp partial nephrectomy in patients with T1 renal tumors | en_US |
dc.type | Article | en_US |
dc.relation.no | 7 | - |
dc.relation.volume | 25 | - |
dc.identifier.doi | 10.1111/iju.13705 | - |
dc.relation.page | 690-697 | - |
dc.relation.journal | INTERNATIONAL JOURNAL OF UROLOGY | - |
dc.contributor.googleauthor | Raheem, Ali Abdel | - |
dc.contributor.googleauthor | Shin, Tae Young | - |
dc.contributor.googleauthor | Chang, Ki Don | - |
dc.contributor.googleauthor | Santok, Glen Denmer R. | - |
dc.contributor.googleauthor | Alenzi, Mohamed Jayed | - |
dc.contributor.googleauthor | Yoon, Young Eun | - |
dc.contributor.googleauthor | Ham, Won Sik | - |
dc.contributor.googleauthor | Han, Woong Kyu | - |
dc.contributor.googleauthor | Choi, Young Deuk | - |
dc.contributor.googleauthor | Rha, Koon Ho | - |
dc.relation.code | 2018010414 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | urologistyoon | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.