Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤영은 | - |
dc.date.accessioned | 2019-11-26T04:24:44Z | - |
dc.date.available | 2019-11-26T04:24:44Z | - |
dc.date.issued | 2017-06 | - |
dc.identifier.citation | TRANSPLANTATION PROCEEDINGS, v. 49, no. 5, page. 930-934 | en_US |
dc.identifier.issn | 0041-1345 | - |
dc.identifier.issn | 1873-2623 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S004113451730249X?via%3Dihub | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/114525 | - |
dc.description.abstract | Background. Hyperuricemia has been associated with kidney disease and remains controversial with regard to its gender-specific differences and impact in living kidney donation.Methods. Between 2006 and 2015, charts of live kidney donors who underwent nephrectomy and had a minimum follow-up of 1 year were reviewed. A total of 291 donors were included and divided based on gender-specific pre-donation serum uric acid (SUA) tertiles. Renal functional outcomes included were estimated glomerular filtration rate (eGFR) at 6-month and 1-year follow-up and percentage of donors with a 1-year eGFR < 60 mL/min/1.72 m(2). Logistic regression analysis was done.Results. Mean SUA tertiles were 5.8 +/- 1.1 mg/dL in males and 4.1 +/- 1 mg/dL in females. Females in the highest tertile (SUA > 4.5 mg/dL) had lower 6-month (59.9 +/- 10.3 vs 66.9 +/- 14.1 vs 67.3 +/- 12.1; P = .018) and 1-year (60.8 +/- 10.6 vs 67.6 +/- 10.8 vs 67.8 +/- 11.8; P = .021) eGFR and a higher percentage of donors with 1-year eGFR < 60 mL/min/1.73 m(2) (59.5% vs 31.6% vs 23%; P = .002) compared with donors in the lower SUA tertiles (<= 4.5 mg/dL). In males, there were similar eGFRs among SUA tertiles at 6-month and 1-year follow-up. In multivariate analysis, SUA was shown to be a significant predictor of developing stage 3 CKD (eGFR < 60 mL/min/1.72 m(2)), 1 year after donation in females but not in males.Conclusions. Predonation SUA level is associated with the development of delayed renal recovery (GFR < 60 mL/min/1.72 m(2)) 1 year after donation in females but not in males. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | ELSEVIER SCIENCE INC | en_US |
dc.subject | DISEASE | en_US |
dc.subject | HYPERURICEMIA | en_US |
dc.subject | ASSOCIATION | en_US |
dc.subject | PROGRESSION | en_US |
dc.subject | MORTALITY | en_US |
dc.subject | SURVIVAL | en_US |
dc.subject | TRANSPLANTATION | en_US |
dc.title | Investigating Serum Uric Acid as a Risk Factor in the Development of Delayed Renal Recovery in Living Kidney Donors. | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1016/j.transproceed.2017.03.034 | - |
dc.relation.journal | TRANSPLANTATION PROCEEDINGS | - |
dc.contributor.googleauthor | Bravo, R. C. | - |
dc.contributor.googleauthor | Gamo, M. B. | - |
dc.contributor.googleauthor | Lee, H. H. | - |
dc.contributor.googleauthor | Yoon, Y. E. | - |
dc.contributor.googleauthor | Han, W. K. | - |
dc.relation.code | 2017001147 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | urologistyoon | - |
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