Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 송무곤 | - |
dc.date.accessioned | 2019-11-25T02:09:32Z | - |
dc.date.available | 2019-11-25T02:09:32Z | - |
dc.date.issued | 2017-05 | - |
dc.identifier.citation | ONCOTARGET, v. 8, no. 45, page. 79337-79346 | en_US |
dc.identifier.issn | 1949-2553 | - |
dc.identifier.uri | http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=18107&path[]=58023 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/113994 | - |
dc.description.abstract | Tumor necrosis (TN) is associated with worse prognosis in several solid cancers. Whether TN predicts poor outcome in natural killer cell / T cell lymphoma (NKTCL) is unclear. We investigated the clinical impact of TN on survival and other novel prognostic parameters in upper aero-digestive tract (UAT) NKTCL of 100 patients with limited stage. TN was significantly associated with poor performance status (p = 0.049), high Korean Prognostic Index score (p = 0.024), high C-reactive protein/albumin ratio (p = 0.003), higher maximum standard uptake value on positron emission tomography/computed tomography (PET/CT) (p = 0.008) and higher metabolic tumor volume (MTV) on PET/CT (p < 0.001). In univariate and multivariate analyses, progression-free survival and overall survival were independently associated with High MTV status (p = 0.001, p = 0.032), TN (p = 0.018, p = 0.009), local tumor invasiveness (p = 0.007, p = 0.035), complete resection (p = 0.020, p = 0.028) and regional lymph node involvement (p < 0.001, p < 0.001). TN and complete resection are concluded to be novel independent prognostic factors in patients with UAT NKTCL. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | IMPACT JOURNALS LLC | en_US |
dc.subject | extranodal natural killer/T-cell lymphoma | en_US |
dc.subject | tumor necrosis | en_US |
dc.subject | complete resection | en_US |
dc.subject | prognosis | en_US |
dc.title | Tumor necrosis and complete resection has significant impacts on survival in patients with limited-stage upper aerodigestive tract NK/T cell lymphoma | en_US |
dc.type | Article | en_US |
dc.relation.no | 45 | - |
dc.relation.volume | 8 | - |
dc.identifier.doi | 10.18632/oncotarget.18107 | - |
dc.relation.page | 79337-79346 | - |
dc.relation.journal | ONCOTARGET | - |
dc.contributor.googleauthor | Song, Moo-Kon | - |
dc.contributor.googleauthor | Chung, Joo-Seop | - |
dc.contributor.googleauthor | Yhim, Ho-Young | - |
dc.contributor.googleauthor | Lim, Sung-Nam | - |
dc.contributor.googleauthor | Kim, Seong-Jang | - |
dc.contributor.googleauthor | Han, Yeon-Hee | - |
dc.contributor.googleauthor | Shim, Hye-Kyung | - |
dc.contributor.googleauthor | Jung, Sung-Hoon | - |
dc.contributor.googleauthor | Lee, Je-Jung | - |
dc.contributor.googleauthor | Yang, Deok-Hwan | - |
dc.relation.code | 2017009424 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | song9676 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.