Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박준성 | - |
dc.date.accessioned | 2019-11-24T17:27:27Z | - |
dc.date.available | 2019-11-24T17:27:27Z | - |
dc.date.issued | 2017-04 | - |
dc.identifier.citation | JOURNAL OF KOREAN MEDICAL SCIENCE, v. 32, no. 4, page. 613-620 | en_US |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.issn | 1598-6357 | - |
dc.identifier.uri | https://synapse.koreamed.org/DOIx.php?id=10.3346/jkms.2017.32.4.613 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/113771 | - |
dc.description.abstract | Abdominal obesity is a major risk factor of chronic kidney disease (CKD). Conventional obesity-related indicators, included body mass index (BMI), waist circumference (WC), and conicity index (C-index), have some limitations. We examined the usefulness of trunk/body fat mass ratio (T/Br) to predict negative effect of abnormal fat distribution on excretory kidney function. We analyzed anthropometric, biochemical and densitometric data from a nation-wide, population-based, case-control study (the Korean National Health and Nutrition Examination Survey [KNHANES] IV and V). A total of 11,319 participants were divided into 2 groups according to estimated glomerular filtration rate (eGFR, mL.min(-1).1.73 m(-2)) as follows: Group I (n= 7,980), eGFR >= 90 and <= 120; and group II (n= 3,339), eGFR >= 60 and < 90. Linear regression analysis revealed that T/Br was closely related to eGFR (beta = -0.3173, P < 0.001), and the correlation remained significant after adjustment for age, gender, BMI, WC, C-index, systolic blood pressure (BP), hemoglobin, and smoking amount (beta = -0.0987, P < 0.001). Logistic regression analysis showed that T/Br (odds ratio [OR] = 1.046; 95% confidence interval [CI] = 1.039-1.054) was significantly associated with early decline of kidney function, and adjustment for age, gender, BMI, C-index, systolic BP, hemoglobin, serum glucose level, high-density lipoprotein (HDL)cholesterol, and smoking amount did not reduce the association (OR = 1.020; 95% CI = 1.007-1.033). T/Br is useful in estimating the negative impact of abdominal obesity on the kidney function. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | en_US |
dc.subject | Abdominal Obesity | en_US |
dc.subject | Densitometry | en_US |
dc.subject | Trunk/Body Fat Mass Ratio | en_US |
dc.subject | Glomerular Filtration Rate | en_US |
dc.title | Estimating Negative Effect of Abdominal Obesity on Mildly Decreased Kidney Function Using a Novel Index of Body-Fat Distribution | en_US |
dc.type | Article | en_US |
dc.relation.no | 4 | - |
dc.relation.volume | 32 | - |
dc.identifier.doi | 10.3346/jkms.2017.32.4.613 | - |
dc.relation.page | 613-620 | - |
dc.relation.journal | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.contributor.googleauthor | Oh, Il Hwan | - |
dc.contributor.googleauthor | Choi, Jong Wook | - |
dc.contributor.googleauthor | Lee, Chang Hwa | - |
dc.contributor.googleauthor | Park, Joon-Sung | - |
dc.relation.code | 2017002851 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | sjpjoon | - |
dc.identifier.orcid | http://orcid.org/0000-0003-4740-3061 | - |
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