Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이경석 | - |
dc.date.accessioned | 2019-10-21T05:39:06Z | - |
dc.date.available | 2019-10-21T05:39:06Z | - |
dc.date.issued | 2019-07 | - |
dc.identifier.citation | ALLERGY ASTHMA & IMMUNOLOGY RESEARCH, v. 11, NO 4, Page. 572-582 | en_US |
dc.identifier.issn | 2092-7355 | - |
dc.identifier.issn | 2092-7363 | - |
dc.identifier.uri | https://e-aair.org/DOIx.php?id=10.4168/aair.2019.11.4.572 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/111271 | - |
dc.description.abstract | Purpose: Children with sensitization to aeroallergens have decreased lung function and nasal patency. Our purpose was to determine the association of sensitization to different aeroallergens with airway function and nasal patency. Methods: Four hundred and eighty-six randomly selected 11 year-old children who lived in Seongnam City were examined. Serum specific immunoglobulin E (IgE) levels against 6 common allergens (Dermatophagoidesfarinae, birch, cat, dog, Japanese hop and Alternaria), impulse oscillometry (IOS) results for the evaluation of airway dysfunction, and acoustic rhinometry for the determination of nasal airway patency were obtained. Results: IOS indicated that children sensitized to Alternaria (n = 38, 7.8%) and dog dander (n = 69,14.2%) had decreased lung function, based on resistance at 10 Hz (Rrs10; a beta = 0.0072; 95% CI, 0.017, 0.127; P= 0.010) and 1 Hz (Rrs1; a beta = 0.038; 95% CI, 0.001, 0.074; P= 0.042). Children sensitized to D. farinae (n = 281, 57.8%) had decreased post-decongestant nasal volume at 0 to 5 cm (a beta = -0.605; 95% CI, -1.005, -0.205; P= 0.003), but normal IOS results at all measured frequencies (P > 0.05). Increased serum eosinophil level was associated with Rrsl (P = 0.007) and Rrs2 (P = 0.018) and post-decongestant nasal volume at 0 to 5 cm (a beta = -0.885; 95% CI, -1.331, -0.439; P < 0.001). Conclusions: Sensitivity to specific aeroallergens, serum eosinophil count and total IgE level had different associations with upper and lower airway dysfunction in urban children. | en_US |
dc.description.sponsorship | This study was supported by a grant from the Seongnam Atopy Project of the Seongnam City Government, Republic of Korea. The funding agencies had no role in the design and conduct of the study; collection, management, analysis, or interpretation of the data; preparation, review, or approval of the manuscript; and the decision to submit the manuscript for publication. We are grateful to the children and families of the study for their support and dedication. We thank the Department of Environment Policy at Seongnam City Government for its assistance and cooperation. | en_US |
dc.language.iso | en | en_US |
dc.publisher | KOREAN ACAD ASTHMA ALLERGY & CLINICAL IMMUNOLOGY | en_US |
dc.subject | Lung function tests | en_US |
dc.subject | oscillometry | en_US |
dc.subject | rhinometry | en_US |
dc.subject | allergens | en_US |
dc.subject | eosinophil count | en_US |
dc.title | Association of Sensitization to Different Aeroallergens With Airway Function and Nasal Patency in Urban Children | en_US |
dc.type | Article | en_US |
dc.relation.no | 4 | - |
dc.relation.volume | 11 | - |
dc.identifier.doi | 10.4168/aair.2019.11.4.572 | - |
dc.relation.page | 572-582 | - |
dc.relation.journal | ALLERGY ASTHMA & IMMUNOLOGY RESEARCH | - |
dc.contributor.googleauthor | Lee, Shinhae | - |
dc.contributor.googleauthor | Koh, Hyun Yong | - |
dc.contributor.googleauthor | Yon, Dong Keon | - |
dc.contributor.googleauthor | Lee, Seung Won | - |
dc.contributor.googleauthor | Ha, Eun Kyo | - |
dc.contributor.googleauthor | Sung, Myongsoon | - |
dc.contributor.googleauthor | Lee, Kyung Suk | - |
dc.contributor.googleauthor | Jee, Hye Mi | - |
dc.contributor.googleauthor | Sheen, Youn Ho | - |
dc.contributor.googleauthor | Han, Man Yong | - |
dc.relation.code | 2019040260 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | noquit | - |
dc.identifier.orcid | https://orcid.org/0000-0002-6300-1348 | - |
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