Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 안유민 | - |
dc.date.accessioned | 2019-05-20T05:44:21Z | - |
dc.date.available | 2019-05-20T05:44:21Z | - |
dc.date.issued | 2008-08 | - |
dc.identifier.citation | 대한기계학회논문집 A, v. 32, No. 8, Page. 624-632 | en_US |
dc.identifier.issn | 1226-4873 | - |
dc.identifier.uri | http://www.dbpia.co.kr/Journal/ArticleDetail/NODE01028250 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/104814 | - |
dc.description.abstract | In this research, we developed new PDMS-glass based microbiochip consisted of the micromixer and microreactor for DNA ligation. The micromixer was composed of a straight channel integrated with nozzles and pillars, and the microreactor was composed of a serpentine channel. We coated the PDMS chip surface with the 0.25wt.% PVP solution to prevent the bubble generation which was caused by the hydrophobicity of the PDMS. The new micomixer was passive type and the mixing was enhanced by a convective diffusion using the nozzle and pillar. The 10.33mm long micromixer showed the good mixing efficiency of 87.7% at 500?l/min flow rate. We could perform the DNA ligation successfully in the microbiochip, and the ligation time was shortened from 4 hours in conventional laboratory method to 5 min in the microbiochip. | en_US |
dc.language.iso | ko_KR | en_US |
dc.publisher | 대한기계학회 | en_US |
dc.subject | Microbiochip(마이크로바이오칩) | en_US |
dc.subject | Micromixer(마이크로혼합기) | en_US |
dc.subject | PVP Coating(PVP 표면처리) | en_US |
dc.subject | DNA Ligation(DNA 결찰) | en_US |
dc.title | 마이크로 혼합기와 반응기로 구성된 DNA 결찰용 바이오칩에 관한 연구 | en_US |
dc.title.alternative | A Study About Biochip Combined with Micro Mixer and Reactor for DNA Ligation | en_US |
dc.type | Article | en_US |
dc.relation.journal | 대한기계학회논문집 A | - |
dc.contributor.googleauthor | 강도형 | - |
dc.contributor.googleauthor | 안유민 | - |
dc.contributor.googleauthor | 황승용 | - |
dc.relation.code | 2012100288 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF ENGINEERING SCIENCES[E] | - |
dc.sector.department | DEPARTMENT OF MECHANICAL ENGINEERING | - |
dc.identifier.pid | ahnym | - |
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