Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정민성 | - |
dc.date.accessioned | 2019-03-26T01:03:37Z | - |
dc.date.available | 2019-03-26T01:03:37Z | - |
dc.date.issued | 2016-11 | - |
dc.identifier.citation | EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, v. 35, Issue 11,Page. 1771-1776 | en_US |
dc.identifier.issn | 0934-9723 | - |
dc.identifier.issn | 1435-4373 | - |
dc.identifier.uri | https://link.springer.com/article/10.1007%2Fs10096-016-2725-6 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/101188 | - |
dc.description.abstract | Purpose The purpose of this study was to investigate the impact of malignancy and chemotherapy on the clinical and microbiological characteristics of Clostridium difficile infections (CDI). Methods CDI patients with a history of malignancy within 5 years were defined as the cancer group. The characteristics of the patients were compared according to the presence of malignancy. Results Of 580 patients with CDI, 159 (27.4 %) belonged to the cancer group and 421 (72.6 %) to the non-cancer group. More of the patients in the cancer group than those in the non-cancer group had been hospitalized within the prior 2 months (P < 0.001). Leukocytosis was more common in the non-cancer group (P = 0.034), while infection by PCR ribotype 017 strains was more common in the cancer group, with marginal significance (P = 0.07). Recurrence was more frequent in the cancer group (20.4 % vs. 9.5 %, P =0.005) and cancer was an independent risk factor for recurrence of CDI (OR = 2.66, 95 % CI 1.34-5.29, P =0.005). Age also contributed to the recurrence of CDI (OR = 1.03, 95 % CI 1.00-1.06, P =0.026). Conclusions Malignancy and age are independent risk factors for recurrence of CDI. Cancer patients require careful observation for recurrence after treatment of CDI. | en_US |
dc.description.sponsorship | This work was supported by the research fund of Hanyang University (HY-2011). | en_US |
dc.language.iso | en | en_US |
dc.publisher | SPRINGER | en_US |
dc.subject | ADULT ONCOLOGY PATIENTS | en_US |
dc.subject | RISK-FACTORS | en_US |
dc.subject | HEALTH-CARE | en_US |
dc.subject | CLINICAL CHARACTERISTICS | en_US |
dc.subject | CANCER-PATIENTS | en_US |
dc.subject | EPIDEMIOLOGY | en_US |
dc.subject | DIARRHEA | en_US |
dc.subject | DISEASE | en_US |
dc.subject | CHEMOTHERAPY | en_US |
dc.subject | BI/NAP1/027 | en_US |
dc.title | Impact of malignancy on Clostridium difficile infection | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1007/s10096-016-2725-6 | - |
dc.relation.journal | EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | - |
dc.contributor.googleauthor | Chung, M. S. | - |
dc.contributor.googleauthor | Kim, J. | - |
dc.contributor.googleauthor | Kang, J. O. | - |
dc.contributor.googleauthor | Pai, H. | - |
dc.relation.code | 2016001618 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | bovie | - |
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