Preparation of alpha-bisabolol and phenylethyl resorcinol/TiO2 hybrid composites for potential applications in cosmetics
- Title
- Preparation of alpha-bisabolol and phenylethyl resorcinol/TiO2 hybrid composites for potential applications in cosmetics
- Author
- 오성근
- Keywords
- chemical analysis; chemical synthesis; formulation
- Issue Date
- 2016-10
- Publisher
- WILEY-BLACKWELL
- Citation
- INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, v. 38, NO. 5, Page. 524-534
- Abstract
- ObjectiveBifunctional alpha-bisabolol and phenylethyl resorcinol/TiO2 hybrids were prepared to apply in cosmetic fields, particularly in anti-ageing and hyperpigmentation treatment. The synergistic effect of combined antioxidant and UV filtering properties was achieved through functionalization of TiO2 particles with skin-lightening materials such as alpha-bisabolol and phenylethyl resorcinol.
MethodsTiO(2) microspheres with a diameter of about 1 m were synthesized through surfactant-assisted sol-gel method for use as supporting materials in the formation of hybrid composites. Carboxylation treatment was performed for surface modification of the TiO2 surface with carboxyl groups as chemical binders. Esterification reaction between carboxyl groups of carboxylated TiO2 and hydroxyl groups of alpha-bisabolol or phenylethyl resorcinol was performed. The hybrids were characterized using various techniques such as FE-SEM, DLS, EDS, ATR-FTIR, XPS and TGA. For application of prepared TiO2 composites in the field of cosmetics, the anti-radicular antioxidant abilities were evaluated using ABTS and DPPH colorimetric antioxidant assay.
ResultsOrganic/inorganic hybrid composites were successfully formed using esterification reaction between the carboxyl groups at TiO2 surface and the hydroxyl groups of the skin-lightening materials. The results demonstrate that both functionalized microspheres show scavenging ability towards the ABTS(center dot) and DPPH center dot radicals. Specifically, the phenylethyl resorcinol/TiO2 composites exhibited the highest antioxidant ability among the prepared samples owing to the presence of phenolic groups to scavenge free radicals.
ConclusionUsing this strategy, it could be possible to prepare not only inorganic UV filter but also hybrid organic/inorganic materials with multifunctions and advantages which would be in a great demand for cosmetic applications.
Resume
ObjectifDes hybrides bifonctionnels d'alpha-bisabolol et de phenylethyle resorcinol/TiO2 ont ete prepares pour des applications dans les domaines cosmetiques, en particulier dans le anti-vieillissement et le traitement de l'hyperpigmentation. L'effet synergique d'antioxydants combines et les proprietes de filtrage UV a ete realise grace a la fonctionnalisation des particules de TiO2 avec des materiaux d'eclaircissement de la peau tels que l'alpha-bisabolol et lephenylethyle resorcinol.
Methodesdes microspheres de TiO2 presentant un diametre d'environ 1 m ont ete synthetises le procede sol-gel assiste par un agent tensio-actif, destine a etre utilise en tant que materiel de support dans la formation des composites hybrides. Un traitement de carboxylation a ete effectue pour la modification de surface de la surface de TiO2 avec des groupes carboxyle comme liants chimiques. Les reactions d'esterification entre les groupes carboxyle de TiO2 et les groupes hydroxyle carboxyles de l'alpha-bisabolol, le resorcinol ou phenylethyle ont ete realisees. Les hybrides ont ete caracterises par differentes techniques telles que FE-SEM, DLS, EDS, ATR-FTIR, XPS et TGA. Pour l'application des composites de TiO2 prepares dans le domaine de la cosmetique, les capacites anti-oxydantes et anti-radicalaires ont ete evalues en utilisant ABTS et le dosage anti-oxydant colorimetrique DPPH.
ResultatsLes composites hybrides organiques/inorganiques ont ete formes avec succes en utilisant une reaction d'esterification entre les groupes carboxyle a la surface de TiO2 et les groupes hydroxyle des materiaux d'eclaircissement de la peau. Les resultats montrent que les microspheres fonctionnalisees montrent la capacite de captage vers l'ABTS(center dot) et les radicaux DPPH center dot. Plus precisement, les materiaux composites phenylethyle resorcinol/TiO2 ont presente la plus forte capacite anti-oxydante, parmi les echantillons prepares en raison de la presence de groupements phenoliques pour pieger les radicaux libres.
ConclusionEn utilisant cette strategie, il pourrait etre possible de preparer non seulement un filtre UV inorganique, mais aussi des matieres organiques / inorganiques hybrides avec des multi-fonctions et avantages qui representent une grande demande dans des applications cosmetiques.
- URI
- https://onlinelibrary.wiley.com/doi/full/10.1111/ics.12339https://repository.hanyang.ac.kr/handle/20.500.11754/99202
- ISSN
- 0142-5463; 1468-2494
- DOI
- 10.1111/ics.12339
- Appears in Collections:
- COLLEGE OF ENGINEERING[S](공과대학) > CHEMICAL ENGINEERING(화학공학과) > Articles
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