Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 송무곤 | - |
dc.date.accessioned | 2019-02-20T00:32:06Z | - |
dc.date.available | 2019-02-20T00:32:06Z | - |
dc.date.issued | 2016-10 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF HEMATOLOGY, v. 104, no. 4, page. 476-484 | en_US |
dc.identifier.issn | 0925-5710 | - |
dc.identifier.issn | 1865-3774 | - |
dc.identifier.uri | https://link.springer.com/article/10.1007%2Fs12185-016-2050-y | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/99073 | - |
dc.description.abstract | Although splenomegaly is major characteristic of primary myelofibrosis (PMF), splenomegaly has been devalued due to a less reliable method based on physical examination (PEx). We evaluated whether spleen volume (SV) on CT would accurately predict clinical outcomes in PMF. A total of 188 patients were enrolled. SV was quantitated by the automatic volume software. In ROC curve, the SV predicted prognosis more accurately than spleen length by PEx (p < 0.001). The ideal cut-off value was 378.1 cm(3) for SV, which was divided into high- and low-volume status. Patients with low SV status had superior leukemia-free survival and overall survival compared to high SV status (p < 0.001, p < 0.001) In the Cox analysis, old age aeyen65 years (p = 0.004, p = 0.001), low Hemoglobin < 10.0 g/dL (p = 0.023, p = 0.021), high WBC counts aeyen25 x 10(9)/L (p = 0.003, p = 0.006), peripheral blasts aeyen1 % (p = 0.029, p = 0.020), unfavorable cytogenetic abnormalities (p = 0.025, p = 0.028), and high SV status (p = 0.004, p = 0.003) were independently associated with survivals. SV measured by CT was important for predicting survival in patients with PMF. | en_US |
dc.language.iso | en | en_US |
dc.publisher | SPRINGER JAPAN KK | en_US |
dc.subject | Primary myelofibrosis | en_US |
dc.subject | Splenomegaly | en_US |
dc.subject | Computed tomography | en_US |
dc.subject | Splenic volume | en_US |
dc.subject | Overall survival | en_US |
dc.title | Usefulness of spleen volume measured by computed tomography for predicting clinical outcome in primary myelofibrosis. | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1007/s12185-016-2050-y | - |
dc.relation.journal | INTERNATIONAL JOURNAL OF HEMATOLOGY | - |
dc.contributor.googleauthor | Song, Moo-Kon | - |
dc.contributor.googleauthor | Chung, Joo-Seop | - |
dc.contributor.googleauthor | Lim, Sung-Nam | - |
dc.contributor.googleauthor | Lee, Gyeong-won | - |
dc.contributor.googleauthor | Lee, Sang-Min | - |
dc.contributor.googleauthor | Lee, Nam-Kyung | - |
dc.contributor.googleauthor | Choi, Jae-Cheol | - |
dc.contributor.googleauthor | Oh, So-Yeon | - |
dc.relation.code | 2016009834 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | song9676 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.