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Emerging potential of stimulus-responsive nanosized anticancer drug delivery systems for systemic applications

Title
Emerging potential of stimulus-responsive nanosized anticancer drug delivery systems for systemic applications
Author
최한곤
Keywords
Nanomedicine; Polymer therapeutics; Drug delivery systems; Stimulus-responsive
Issue Date
2018-02
Publisher
PHARMACEUTICAL SOC KOREA
Citation
ARCHIVES OF PHARMACAL RESEARCH, v. 41, No. 2, Page. 111-129
Abstract
The development of novel drug delivery systems based on well-defined polymer therapeutics has led to significant improvements in the treatment of multiple disorders. Advances in material chemistry, nanotechnology, and nanomedicine have revolutionized the practices of drug delivery. Stimulus-responsive material-based nanosized drug delivery systems have remarkable properties that allow them to circumvent biological barriers and achieve targeted intracellular drug delivery. Specifically, the development of novel nanocarrier-based therapeutics is the need of the hour in managing complex diseases. In this review, we have briefly described the fundamentals of drug targeting to diseased tissues, physiological barriers in the human body, and the mechanisms/modes of drug-loaded carrier systems. To that end, this review serves as a comprehensive overview of the recent developments in stimulus-responsive drug delivery systems, with focus on their potential applications and impact on the future of drug delivery.
URI
https://link.springer.com/article/10.1007%2Fs12272-017-0995-xhttps://repository.hanyang.ac.kr/handle/20.500.11754/80913
ISSN
0253-6269
DOI
10.1007/s12272-017-0995-x
Appears in Collections:
COLLEGE OF PHARMACY[E](약학대학) > PHARMACY(약학과) > Articles
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