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dc.contributor.author최호순-
dc.date.accessioned2018-10-10T06:25:26Z-
dc.date.available2018-10-10T06:25:26Z-
dc.date.issued2016-08-
dc.identifier.citationPANCREAS, v. 45, NO. 7, Page. 941-946en_US
dc.identifier.issn0885-3177-
dc.identifier.issn1536-4828-
dc.identifier.urihttps://oce.ovid.com/article/00006676-201608000-00003-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/76409-
dc.description.abstractObjectives: Pancreatic neuroendocrine tumors (pNETs) are diverse diseases with different prognosis. The American Joint Committee on Cancer (AJCC) and the European Neuroendocrine Tumor Society (ENETS) introduced 2 different tumor node metastasis (TNM) stages, and the World Health Organization (WHO) proposed WHO 2010 grading system for pNETs. Therefore, we aimed to validate the prognostic relevance of these 3 systems for pNETs in South Korea. Methods: The Korean Society of Gastrointestinal Cancer created a retrospective registry of pNETs in 153 patients from 15 hospitals between 2002 and 2012. Results: On the basis of the WHO 2010 grade, 2-year progression-free-survival (PFS) rates for G1, G2, and G3 were 92%, 62%, and 25% (P ˂ 0.01). According to ENETS and AJCC staging, 2-year PFS rates for stages I through IV were 94%, 87%, 49%, 20%, and 92%, 61%, 60%, 20%, respectively (P ˂ 0.01). A Cox multivariate regression analysis revealed that the only statistically significant prognostic factor was the TNM classification of either the AJCC or the ENETS stage (P ˂ 0.01). In addition, the. value between the AJCC and the ENETS stages was 0.46 indicating a "moderate" agreement (P ˂ 0.01). Conclusions: The AJCC and ENETS TNM classifications for pNETs are prognostic for PFS and can be adopted in clinical practice in South Korea.en_US
dc.language.isoenen_US
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.subjectpancreatic neuroendocrine tumorsen_US
dc.subjectprognosisen_US
dc.subjectgradingen_US
dc.subjectstagingen_US
dc.titlePrognostic Validity of the American Joint Committee on Cancer and the European Neuroendocrine Tumors Staging Classifications for Pancreatic Neuroendocrine Tumors A Retrospective Nationwide Multicenter Study in South Koreaen_US
dc.typeArticleen_US
dc.relation.no7-
dc.relation.volume45-
dc.identifier.doi10.1097/MPA.0000000000000586-
dc.relation.page941-946-
dc.relation.journalPANCREAS-
dc.contributor.googleauthorCho, Jae Hee-
dc.contributor.googleauthorRyu, Ji Kon-
dc.contributor.googleauthorSong, Si Young-
dc.contributor.googleauthorHwang, Jin-Hyeok-
dc.contributor.googleauthorLee, Dong Ki-
dc.contributor.googleauthorWoo, Sang Myung-
dc.contributor.googleauthorJoo, Young-Eun-
dc.contributor.googleauthorJeong, Seok-
dc.contributor.googleauthorLee, Seung-Ok-
dc.contributor.googleauthorChoi, Ho Soon-
dc.relation.code2016001081-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidhschoi96-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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