Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최호순 | - |
dc.date.accessioned | 2018-10-10T06:25:26Z | - |
dc.date.available | 2018-10-10T06:25:26Z | - |
dc.date.issued | 2016-08 | - |
dc.identifier.citation | PANCREAS, v. 45, NO. 7, Page. 941-946 | en_US |
dc.identifier.issn | 0885-3177 | - |
dc.identifier.issn | 1536-4828 | - |
dc.identifier.uri | https://oce.ovid.com/article/00006676-201608000-00003 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/76409 | - |
dc.description.abstract | Objectives: Pancreatic neuroendocrine tumors (pNETs) are diverse diseases with different prognosis. The American Joint Committee on Cancer (AJCC) and the European Neuroendocrine Tumor Society (ENETS) introduced 2 different tumor node metastasis (TNM) stages, and the World Health Organization (WHO) proposed WHO 2010 grading system for pNETs. Therefore, we aimed to validate the prognostic relevance of these 3 systems for pNETs in South Korea. Methods: The Korean Society of Gastrointestinal Cancer created a retrospective registry of pNETs in 153 patients from 15 hospitals between 2002 and 2012. Results: On the basis of the WHO 2010 grade, 2-year progression-free-survival (PFS) rates for G1, G2, and G3 were 92%, 62%, and 25% (P ˂ 0.01). According to ENETS and AJCC staging, 2-year PFS rates for stages I through IV were 94%, 87%, 49%, 20%, and 92%, 61%, 60%, 20%, respectively (P ˂ 0.01). A Cox multivariate regression analysis revealed that the only statistically significant prognostic factor was the TNM classification of either the AJCC or the ENETS stage (P ˂ 0.01). In addition, the. value between the AJCC and the ENETS stages was 0.46 indicating a "moderate" agreement (P ˂ 0.01). Conclusions: The AJCC and ENETS TNM classifications for pNETs are prognostic for PFS and can be adopted in clinical practice in South Korea. | en_US |
dc.language.iso | en | en_US |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | en_US |
dc.subject | pancreatic neuroendocrine tumors | en_US |
dc.subject | prognosis | en_US |
dc.subject | grading | en_US |
dc.subject | staging | en_US |
dc.title | Prognostic Validity of the American Joint Committee on Cancer and the European Neuroendocrine Tumors Staging Classifications for Pancreatic Neuroendocrine Tumors A Retrospective Nationwide Multicenter Study in South Korea | en_US |
dc.type | Article | en_US |
dc.relation.no | 7 | - |
dc.relation.volume | 45 | - |
dc.identifier.doi | 10.1097/MPA.0000000000000586 | - |
dc.relation.page | 941-946 | - |
dc.relation.journal | PANCREAS | - |
dc.contributor.googleauthor | Cho, Jae Hee | - |
dc.contributor.googleauthor | Ryu, Ji Kon | - |
dc.contributor.googleauthor | Song, Si Young | - |
dc.contributor.googleauthor | Hwang, Jin-Hyeok | - |
dc.contributor.googleauthor | Lee, Dong Ki | - |
dc.contributor.googleauthor | Woo, Sang Myung | - |
dc.contributor.googleauthor | Joo, Young-Eun | - |
dc.contributor.googleauthor | Jeong, Seok | - |
dc.contributor.googleauthor | Lee, Seung-Ok | - |
dc.contributor.googleauthor | Choi, Ho Soon | - |
dc.relation.code | 2016001081 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | hschoi96 | - |
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