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dc.contributor.author이수언-
dc.date.accessioned2018-09-03T07:15:16Z-
dc.date.available2018-09-03T07:15:16Z-
dc.date.issued2016-07-
dc.identifier.citationJOURNAL OF CLINICAL NEUROSCIENCE, v. 29, page 121-127en_US
dc.identifier.issn0967-5868-
dc.identifier.issn1532-2653-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0967586815007079?via%3Dihub-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/74711-
dc.description.abstractWe conducted a prospective randomized study comparing stand-alone cage and bone autograft and plate implants in anterior cervical discectomy and fusion (www.clinicaltrials.gov, NCT01011569). Our interim analysis showed autologous bone graft with plating was superior to a stand-alone cage for segmental lordosis. During this analysis, we noted a difference in canal encroachment by the fusion mass between the two fusion groups. A narrow cervical spinal canal is an important factor in the development of cervical spondylotic myelopathy, therefore this unexpected potential risk of spinal cord compression necessitated another interim analysis to investigate whether there was a difference in canal encroachment by the fusion mass between the two groups. Patients had a minimum 1 year of follow-up. The Neck Disability Index, neck and arm pain Visual Analog Scales and lateral radiographs, including bone fusion patterns, were evaluated. Twenty-seven (16 males, 11 females, mean age 54.8 years) and 31 (24 males, seven females, mean age 54.5 years) patients were in the cage and plate group, respectively. Both groups improved after surgery. Fusion began at 2.6 months and 1.3 months and finished at 6.7 months and 4.0 months in 24 (88.9%) and 28 (90.3%) patients in the cage and plate group, respectively. Encroachment into the spinal canal by the fusion mass was significantly different between the fusion types, occuring in 21 (77.8%) patients in the cage group versus six (19.4%) in the plate group (p = 0.003). There was a high incidence of spinal canal encroachment by the fusion mass in the standalone cage group, possibly limiting use in narrow spinal canals. (c) 2015 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipThe authors would like to thank Myunghee Cho Paik, Ph.D. at the Department of Statistics, Seoul National University for statistical consultation. In addition, we would like to thank the Medical Research Collaborating Center at the Seoul National University Hospital and the Seoul National University College of Medicine for their help with statistical analysis. This work was supported by the Global Frontier R&D Program on <Human-centered Interaction for Coexistence> funded by the National Research Foundation of Korea grant funded by the Korean Government (MEST) (NRF-2012M3A6A3055889).en_US
dc.language.isoenen_US
dc.publisherELSEVIER SCI LTDen_US
dc.subjectAdverse effectsen_US
dc.subjectCervical spineen_US
dc.subjectDiscectomyen_US
dc.subjectSpinal fusionen_US
dc.titleDifference in canal encroachment by the fusion mass between anterior cervical discectomy and fusion with bone autograft and anterior plating, and stand-alone cageen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.jocn.2015.10.039-
dc.relation.journalJOURNAL OF CLINICAL NEUROSCIENCE-
dc.contributor.googleauthorLee, Soo Eon-
dc.contributor.googleauthorChung, Chun Kee-
dc.contributor.googleauthorKim, Chi Heon-
dc.relation.code2016010003-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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