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Polyuria with the Concurrent manifestation of Central Diabetes Insipidus (CDI) & Type 2 Diabetes Mellitus (DM)

Title
Polyuria with the Concurrent manifestation of Central Diabetes Insipidus (CDI) & Type 2 Diabetes Mellitus (DM)
Author
한상웅
Keywords
Polyuria; Central diabetes insipidus; Type 2 diabetes mellitus; Water deprivation test
Issue Date
2012-12
Publisher
대한전해질학회
Citation
Electrolytes & Blood Pressure, 2012, 10(1), P.26-30
Abstract
We report a rare case of the concurrent manifestation of central diabetes insipidus (CDI) and type 2 diabetes mellitus (DM). A 56 year-old man was diagnosed as a type 2 DM on the basis of hyperglycemia with polyuria and polydipsia at a local clinic two months ago and started an oral hypoglycemic medication, but resulted in no symptomatic improvement at all. Upon admission to the university hospital, the patient`s initial fasting blood sugar level was 140mg/dL, and he showed polydipsic and polyuric conditions more than 8 L urine/day. Despite the hyperglycemia controlled with metformin and diet, his symptoms persisted. Further investigations including water deprivation test confirmed the coexisting CDI of unknown origin, and the patient`s symptoms including an intense thirst were markedly improved by desmopressin nasal spray (10 μg/day). The possibility of a common origin of CDI and type 2 DM is raised in a review of the few relevant adult cases in the literature.
URI
https://synapse.koreamed.org/DOIx.php?id=10.5049/EBP.2012.10.1.26https://repository.hanyang.ac.kr/handle/20.500.11754/73772
ISSN
1738-5997; 2092-9935
DOI
10.5049/EBP.2012.10.1.26
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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