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Diagnosis of Clinically Significant Portal Hypertension in Patients with Cirrhosis: Splenic Arterial Resistive Index versus Liver Stiffness Measurement

Title
Diagnosis of Clinically Significant Portal Hypertension in Patients with Cirrhosis: Splenic Arterial Resistive Index versus Liver Stiffness Measurement
Author
김태엽
Keywords
Portal hypertension; Doppler ultrasonography; Liver stiffness; Splenomegaly; Resistive index
Issue Date
2016-06-01
Publisher
ELSEVIER SCIENCE INC
Citation
ULTRASOUND IN MEDICINE AND BIOLOGY, v. 42, NO 6, Page. 1312-1320
Abstract
The purpose of the present study is to compare the diagnostic accuracy of the splenic arterial resistive index (SARI) with that of liver stiffness measurement (LSM) for identifying patients with clinically significant portal hypertension (CSPH). We included 47 patients (M:F = 37:10) who underwent Doppler ultrasonography, LSM and hepatic venous pressure gradient (HVPG) on the same day. We investigated whether the SARI and LSM were correlated with the HVPG, and compared area under the curve (AUC) values for the abilities of SARI and LSM to diagnose CSPH. We also performed a sub-group analysis. The SARI and LSM were all moderately correlated with HVPG overall in patients. The AUC of SARI and LSM were 0.873 and 0.745, respectively. In patients without splenomegaly, SARI was strongly correlated with HVPG (r = 0.830), but LSM was moderately correlated with HVPG (r = 0.601). The AUC was also higher for SARI than for LSM. Therefore, SARI is potentially an excellent non-invasive measurement method for diagnosing CSPH, especially those without splenomegaly.
URI
https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S0301562916000594?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0301562916000594%3Fshowall%3Dtrue&referrer=https://repository.hanyang.ac.kr/handle/20.500.11754/73358
ISSN
0301-5629; 1879-291X
DOI
https://doi.org/10.1016/j.ultrasmedbio.2016.01.026
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RESEARCH INSTITUTE[S](부설연구소) > ETC
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