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Comparison of the diagnostic performance of digital breast tomosynthesis and magnetic resonance imaging added to digital mammography in women with known breast cancers

Title
Comparison of the diagnostic performance of digital breast tomosynthesis and magnetic resonance imaging added to digital mammography in women with known breast cancers
Author
구혜령
Keywords
Magnetic resonance imaging; Imaging; Three-dimensional, mammography; Breast neoplasms/pathology; Sensitivity and specificity
Issue Date
2016-06
Publisher
SPRINGER
Citation
EUROPEAN RADIOLOGY, v. 26, NO 6, Page. 1556-1564
Abstract
To compare the diagnostic performance of digital breast tomosynthesis (DBT) and magnetic resonance imaging (MRI) added to mammography in women with known breast cancers. Three radiologists independently reviewed image sets of 172 patients with 184 cancers; mammography alone, DBT plus mammography and MRI plus mammography, and scored for cancer probability using the Breast Imaging Reporting and Data System (BI-RADS). Jack-knife alternative free-response receiver-operating characteristic (JAFROC), which allows diagnostic performance estimation using single lesion as a statistical unit in a cancer-only population, was used. Sensitivity and positive predictive value (PPV) were compared using the McNemar and Fisher-exact tests. The JAFROC figures of merit (FOMs) was lower in DBT plus mammography (0.937) than MRI plus mammography (0.978, P = 0.0006) but higher than mammography alone (0.900, P = 0 .0013). The sensitivity was lower in DBT plus mammography (88.2 %) than MRI plus mammography (97.8 %) but higher than mammography alone (78.3 %, both P < 0 .0001). The PPV was significantly higher in DBT plus mammography (93.3 %) than MRI plus mammography (89.6 %, P = 0 .0282). DBT provided lower diagnostic performance than MRI as an adjunctive imaging to mammography. However, DBT had higher diagnostic performance than mammography and higher PPV than MRI. aEuro cent Digital breast tomosynthesis (DBT) plus mammography was compared with MRI plus mammography. aEuro cent DBT had lower sensitivity and higher PPV than MRI. aEuro cent DBT had higher diagnostic performance than mammography.
URI
https://link.springer.com/article/10.1007%2Fs00330-015-3998-3https://repository.hanyang.ac.kr/handle/20.500.11754/73141
ISSN
0938-7994; 1432-1084
DOI
10.1007/s00330-015-3998-3
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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