Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박진규 | - |
dc.date.accessioned | 2018-06-11T00:46:50Z | - |
dc.date.available | 2018-06-11T00:46:50Z | - |
dc.date.issued | 2016-06 | - |
dc.identifier.citation | BMC NEUROLOGY, v. 16, Page. 113-119 | en_US |
dc.identifier.issn | 1471-2377 | - |
dc.identifier.uri | https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-016-0645-9 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/71949 | - |
dc.description.abstract | Background: This study aimed to determine the risk of thromboembolic events in patients with junctional bradycardia(JB). Methods: We retrospectively reviewed electrocardiograms(ECGs) for 380,682 patients. Those with JB on an ECG at least twice over a >= 3-month interval were included for analysis. We additionally included 138 CHADS(2) score-matched patients(age, 68.4 +/- 15.7 years; male, 52.2 %) in sinus rhythm as a control group. Between the JB patients(with or without retrograde P wave) and controls, we compared incidences of ischemic stroke and a composite of ischemic stroke, renal infarction, ischemic colitis, acute limb ischemia, and pulmonary embolism. Results: Among 380,682 patients (age, 47.6 +/- 19.9 years; male, 49.3 %), 69 patients (age, 68.5 +/- 16.5 years; male, 50.7 %) exhibited JB on an ECG at least twice over a >= 3-month interval; the overall prevalence of JB was 0.02 %. The mean follow-up period was 27.2 +/- 26.2 months. Forty-five patients (65.2 %) in the JB group had no retrograde P wave. Ischemic stroke incidence was significantly higher in JB patients without a retrograde P wave than in controls (6/45 patients [13.3 %] and 3/138 patients [2.2 %], respectively; P = 0.007). The incidence of composite thromboembolic events was also significantly higher in JB patients without a retrograde P wave than in controls (8/45 patients [17.8 %] and 4/138 patients [2.9 %], respectively; P = 0.011). In a Cox proportional hazards model, JB patients without a P wave showed a greater incidence of stroke (hazard ratio, 8.89 [2.20-33.01], P = 0.007) than controls and JB patients with a P wave. Conclusions: Junctional bradycardia is potentially associated with ischemic stroke, particularly in the absence of an identifiable retrograde P wave. | en_US |
dc.language.iso | en | en_US |
dc.publisher | BIOMED CENTRAL LTD | en_US |
dc.subject | Junctional bradycardia | en_US |
dc.subject | Thromboembolic events | en_US |
dc.subject | Stroke | en_US |
dc.title | Junctional bradycardia is a potential risk factor of stroke | en_US |
dc.type | Article | en_US |
dc.relation.volume | 16 | - |
dc.identifier.doi | 10.1186/s12883-016-0645-9 | - |
dc.relation.page | 113-119 | - |
dc.relation.journal | BMC NEUROLOGY | - |
dc.contributor.googleauthor | Kim, Gwang Sil | - |
dc.contributor.googleauthor | Uhm, Jae-Sun | - |
dc.contributor.googleauthor | Kim, Tae-Hoon | - |
dc.contributor.googleauthor | Lee, Hancheol | - |
dc.contributor.googleauthor | Park, Junbeom | - |
dc.contributor.googleauthor | Park, Jin-Kyu | - |
dc.contributor.googleauthor | Joung, Boyoung | - |
dc.contributor.googleauthor | Pak, Hui-Nam | - |
dc.contributor.googleauthor | Lee, Moon-Hyoung | - |
dc.relation.code | 2016010159 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | cardiohy | - |
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