Diffuse-type giant cell tumor of tendon sheath occurring in the subcutaneous tissue of buttock

Abstract

Diffuse-type giant cell tumor of tendon sheath is an uncommon subtype of giant cell tumor of tendon sheath that shows destructive proliferation of synovial-like mononuclear cells, admixed with multinucleate giant cells, foam cells, siderophages and inflammatory cells. This tumor is commonly located in the periarticular soft tissues of knee, thigh and foot, but on rare occasions it can be purely subcutaneous or intramuscular. Diffuse-type giant cell tumor of tendon sheath affecting the buttock is extremely rare and only two cases, periarticular and intramuscular, have been described in the literature. We report the case of a 63-year-old male with diffuse-type giant cell tumor on the subcutaneous tissue of buttock.