Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김교상 | - |
dc.date.accessioned | 2018-04-25T10:59:32Z | - |
dc.date.available | 2018-04-25T10:59:32Z | - |
dc.date.issued | 2011-10 | - |
dc.identifier.citation | Anesthesia and pain medicine, Vol.6, No.4 [2011], pp. 307-313 | en_US |
dc.identifier.issn | 1975-5171 | - |
dc.identifier.uri | http://www.anesth-pain-med.org/journal/view.html?volume=6&number=4&spage=307 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/70476 | - |
dc.description.abstract | An ideal reversal agent could be given at any time after the administration of a neuromuscular blocking agent, and should have no muscarinic side-effects. Sugammadex is a modified γ-cyclodextrin designed to encapsulate rocuronium bromide, providing a rapid reversal of neuromuscular blockade. Sugammadex is a revolutionary investigational reversal drug currently undergoing Phase III testing whose introduction into clinical practice in Korea may change the face of clinical neuromuscular pharmacology. The dose of sugammadex for reversal of moderate block (when T2 is detectable) is approximately 2 mg/kg, the dose is 4?8 mg/kg for profound block (post-tetanic count 1?2) and a larger dose of 16mg/kg for immediate reversal. The use of sugammadex has not been reported to be associated with recurrence of block provided a dose that is adequate for reversal has been used. Sugammadex appears to have an acceptable safety profile. Volatile agent such as sevoflurane seems not to influence the sugammadex ability to reverse the rocuronium neuromuscular blockade. | en_US |
dc.language.iso | ko_KR | en_US |
dc.publisher | 대한마취통증의학회 | en_US |
dc.subject | 근이완제 | en_US |
dc.subject | Neuromuscular block antagonists | en_US |
dc.subject | Sugammadex | en_US |
dc.title | Sugammadex의 임상사용 | en_US |
dc.title.alternative | Clinical use of sugammadex | en_US |
dc.type | Article | en_US |
dc.relation.no | 4 | - |
dc.relation.volume | 6 | - |
dc.relation.page | 307-313 | - |
dc.relation.journal | ANESTHESIA AND PAIN MEDICINE | - |
dc.contributor.googleauthor | 김교상 | - |
dc.relation.code | 2012220625 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | kimks | - |
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