Osteoporosis and Decrease in Bone Mineral Density Have associated with the Reduced Quality Of Life.

Abstract

Objectives: There are lack of study for the association between osteoporosis and reduced quality of life in Korean. In this study, the association between osteoporosis and reduced quality of life were analyzed.Methods: We used the data from the fourth Korea National Health and Nutrition Examination Survey (KNHNES), and 891 women were enrolled who were over the age of 50. Bone mineral density was measured by dual-energy X-ray absorptiometry. The quality of life were measured EuroQol-5 Dimension (EQ-5D).Results: The quality of life of osteoporosis patients, were reduced in all dimensions of EQ-5D, except EuroQol;anxiety and depression. However, EuroQol; anxiety depression side (P=0.05) and VAS (P=0.039) of EQ-5D had significant difference among osteoporosis, osteopenia, and normal group even after adjusted with age, weight, waist circumference, and blood levels of vitamin D. In addition, bone density and EQ-5D utility values had positive association even after adjusted with age and weight, waist circumference, blood levels of vitamin D (R2=0.137, B=0.148, P=0.011).Conclusions: The elderly women with osteoporosis were significantly associated with decreased quality of life. Thus, the quality of life should be considered in treating of osteoporosis patients.