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Recent advances in enzyme immobilization techniques: Metal-organic frameworks as novel substrates

Title
Recent advances in enzyme immobilization techniques: Metal-organic frameworks as novel substrates
Author
Deep, Akash
Keywords
Metal organic frameworks; Enzymes; Biocatalytic supports; Immobilization; Diffusion; Encapsulation
Issue Date
2016-05
Publisher
ELSEVIER SCIENCE SA
Citation
COORDINATION CHEMISTRY REVIEWS, v.322, Page. 30-40
Abstract
In the past few years, metal organic frameworks (MOFs) have drawn increasing research interest as bioimmobilization support materials. The unique properties of MOFs, including tunable porosity, desirable functionality, extremely high surface area, and chemical/thermal stability, have motivated a considerable interest in exploiting them as a potential matrix for enzyme immobilization. Improvements in the biocatalyst efficiency, promising recyclability, enhanced accessibility to active sites, and a high loading capacity are the main features of the novel MOF-enzyme supports. This review aims to cover the recent progress in the application of MOFs as enzyme immobilization supports. We discuss different approaches used in the development of MOF-enzyme biocatalytic supports, such as surface adsorption, diffusion, and in-situ encapsulation. The trends in current developments and the significance of each strategy are critically reviewed in this paper. (C) 2016 Elsevier B.V. All rights reserved.
URI
https://www.sciencedirect.com/science/article/pii/S0010854516301023?via%3Dihubhttp://hdl.handle.net/20.500.11754/68068
ISSN
0010-8545; 1873-3840
DOI
10.1016/j.ccr.2016.05.007
Appears in Collections:
COLLEGE OF ENGINEERING[S](공과대학) > CIVIL AND ENVIRONMENTAL ENGINEERING(건설환경공학과) > Articles
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