Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최정혜 | - |
dc.date.accessioned | 2018-04-16T03:46:13Z | - |
dc.date.available | 2018-04-16T03:46:13Z | - |
dc.date.issued | 2012-10 | - |
dc.identifier.citation | BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, OCT 2012, 18(10), p1500-p1508, 9p. | en_US |
dc.identifier.issn | 1083-8791 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S1083879112001383 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/67704 | - |
dc.description.abstract | Although younger age is associated with favorable prognosis in adults undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) for aplastic anemia (AA), other pretransplantation factors may be more important than age. We retrospectively analyzed the impact of older age on transplantation outcomes and survival in a total of 225 adult patients with AA who underwent allo-HSCT: 57 patients >40 years old (older patient group [OPG]) and 168 patients ≤40 years old (younger patient group [YPG]). Age at allo-HSCT ≤40 years, time from diagnosis to allo-HSCT ≤6 months, and matched related donor (MRD) were favorable prognostic factors in all study patients. Risk analysis of survival in the OPG showed that age >50 years was the only poor prognostic factor. Survival did not differ significantly between the YPG and patients <50 years old in the OPG. In conclusion, patients between the ages of 41 and 50 years with severe AA and MRDs should undergo allo-HSCT as early as possible to optimize survival. | en_US |
dc.description.sponsorship | This work was supported by Priority Research Center Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2010-0029621). | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Science B. V. Amsterdam | en_US |
dc.subject | Aplastic anemia | en_US |
dc.subject | Allogeneic hematopoietic stem cell transplantation | en_US |
dc.subject | Elderly | en_US |
dc.title | Allogeneic Hematopoietic Stem Cell Transplant for Adults over 40 Years Old with Acquired Aplastic Anemia | en_US |
dc.type | Article | en_US |
dc.relation.no | 10 | - |
dc.relation.volume | 18 | - |
dc.identifier.doi | 10.1016/j.bbmt.2012.03.015 | - |
dc.relation.page | 1500-1508 | - |
dc.relation.journal | BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION | - |
dc.contributor.googleauthor | Kim, H. | - |
dc.contributor.googleauthor | Lee, K. H. | - |
dc.contributor.googleauthor | Yoon, S. S. | - |
dc.contributor.googleauthor | Sohn, S. K. | - |
dc.contributor.googleauthor | Joo, Y. D. | - |
dc.contributor.googleauthor | Kim, S. H. | - |
dc.contributor.googleauthor | Kim, B. S. | - |
dc.contributor.googleauthor | Choi, J. H. | - |
dc.contributor.googleauthor | Kwak, J. Y. | - |
dc.contributor.googleauthor | Hyun, M. S. | - |
dc.relation.code | 2012201306 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | jhcmd | - |
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