Agitation; Alternative splicing; GABAA receptor; Gamma 2 subunit; Midazolam; Sevoflurane
Issue Date
2011-06
Publisher
대한마취통증의학회
Citation
Korean journal of anesthesiology, 2011, 60(2), pp.109 - 118
Abstract
Emergence agitation after sevoflurane anesthesia in children can be prevented by midazolam. Alternative splicing of the GABA(A) receptor changes with age. Therefore, we hypothesized that alternative splicing of the γ2 subunit affects the GABA current when applying sevoflurane and midazolam.