Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes
- Title
- Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes
- Author
- 임동우
- Keywords
- Carcinoembryonic Antigen; blood; Gold; chemistry; Humans; Immunoassay; methods; Lung Neoplasms; Metal Nanoparticles; Spectrum Analysis, Raman; Time Factors; Tumor Markers; Biological; alpha-Fetoproteins; analysis
- Issue Date
- 2011-12
- Publisher
- Royal Society of Chemistry
- Citation
- Chemical Communications, 14 December 2011, 47(46), p.12515-12517
- Abstract
- A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility. Graphic Abstract A quick and reproducible SERS-based immunoassay, using hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.
- URI
- http://pubs.rsc.org/en/Content/ArticleLanding/2011/CC/c1cc15707h#!divAbstracthttp://hdl.handle.net/20.500.11754/65868
- ISSN
- 1359-7345; 1364-548X
- DOI
- 10.1039/c1cc15707h
- Appears in Collections:
- GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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