Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 이창범 | - |
dc.date.accessioned | 2018-04-02T07:15:47Z | - |
dc.date.available | 2018-04-02T07:15:47Z | - |
dc.date.issued | 2011-08 | - |
dc.identifier.citation | The Journal of asthma, Feb 2011, 48,2, P.177-182 | en_US |
dc.identifier.issn | 0277-0903 | - |
dc.identifier.issn | 1532-4303 | - |
dc.identifier.uri | http://www.tandfonline.com/doi/abs/10.3109/02770903.2010.529223?journalCode=ijas20 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/54871 | - |
dc.description.abstract | Background. Epidemiological studies have shown that obesity//adiposity is closely associated with asthma in terms of development, severity, and control of asthma. However, effects of obesity//adiposity on airway inflammation are not well known in subjects without asthma. We assessed whether fractional exhaled nitric oxide (FeNO), a marker of eosinophilic airway inflammation, was associated with obesity//adiposity in nonasthmatic healthy adults. Methods. We measured FeNO and serum levels of adipose-derived hormones and adipokines in 117 adult subjects without a previous diagnosis of asthma or current asthmatic symptoms. Associations between FeNO and measures of obesity//adiposity [body mass index (BMI), body fat mass, and body fat percentages] were examined by correlation analyses and uni- and multivariate linear regression analyses. Results. FeNO was not significantly associated with BMI, body fat mass, or body fat percentage by a multivariate linear regression model, adjusting for age, gender, chronic rhinitis, atopy, and lung function. No significant association of FeNO with serum levels of leptin, adiponectin, tumor necrosis factor (TNF)-alpha alpha, or interleukin (IL)-6 was observed. Conclusions. These findings suggest that in healthy subjects without asthma, obesity//adiposity has no significant effect on eosinophilic airway inflammation and that hormones and systemic inflammation derived from adipose tissue do not affect eosinophilic airway inflammation.˂/. | - |
dc.language.iso | en | en_US |
dc.publisher | Informa Healthcare | en_US |
dc.title | Adiposity, Adipokines, and Exhaled Nitric Oxide in Healthy Adults Without Asthma | en_US |
dc.type | Article | en_US |
dc.relation.no | 2 | - |
dc.relation.volume | 48 | - |
dc.identifier.doi | 10.3109/02770903.2010.529223 | - |
dc.identifier.doi | 10.3109/02770903.2010.529223 | - |
dc.relation.page | 177-182 | - |
dc.relation.journal | JOURNAL OF ASTHMA | - |
dc.contributor.googleauthor | KimKim, Sang Heon Sang Heon | - |
dc.contributor.googleauthor | KimKim, Tae Hyung Tae Hyung | - |
dc.contributor.googleauthor | LeeLee, Ji Seon Ji Seon | - |
dc.contributor.googleauthor | KooKoo, Tai Yeon Tai Yeon | - |
dc.contributor.googleauthor | LeeLee, Chang Beom Chang Beom | - |
dc.contributor.googleauthor | YoonYoon, Ho Joo Ho Joo | - |
dc.contributor.googleauthor | ShinShin, Dong Ho Dong Ho | - |
dc.contributor.googleauthor | ParkPark, Sung Soo Sung Soo | - |
dc.contributor.googleauthor | SohnSohn, Jang Won Jang Won | - |
dc.relation.code | 2011204696 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | lekang | - |
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