Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 최보율 | - |
dc.date.accessioned | 2018-03-27T02:52:16Z | - |
dc.date.available | 2018-03-27T02:52:16Z | - |
dc.date.issued | 2013-04 | - |
dc.identifier.citation | FASE Journal, 2014, 27, P.1, 767-776 | en_US |
dc.identifier.issn | 1590-3729 | - |
dc.identifier.issn | 0939-4753 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0939475314000568 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/52918 | - |
dc.description.abstract | Background and aims Arterial stiffness and increased intima-media wall thickness are two of the main predictors of cardiovascular disease (CVD). We evaluated whether brachial-ankle pulse wave velocity (baPWV) and common carotid artery intima-media wall thickness (CCA-IMT) are correlated with alcohol consumption in a cross-sectional study among Korean men and women aged 40 years and over. Methods and results All 5539 subjects (2121 men and 3418 women) were participants in the Multi-Rural Communities cohort (MRcohort) study, a part of the Korean Genome Epidemiology Study (KoGES). The baPWV was positively correlated with alcohol consumption in men (p for trend <0.0001). Age (middle-aged versus elderly) modified the effect of alcohol consumption on PWV. On the other hand CCA-IMT decreased with alcohol consumption in men. There was no favorable zone of alcohol consumption in terms of baPWV and CCA-IMT. Adjustment for lipid profiles substantially attenuated the relationship between alcohol consumption and CCA-IMT. There was no clear relation between alcohol consumption and baPWV/CCA-IMT in women. Conclusions Along with a linear harmful relationship between alcohol consumption and arterial stiffness in men there may also be a beneficial relationship between alcohol consumption and carotid intima-wall thickness. The effect of alcohol on arterial stiffness may be slightly stronger in elderly men, and the effect of alcohol on CCA-IMT may be mediated by lipid factors. | en_US |
dc.description.sponsorship | Arterial stiffness and increased intima-media wall thickness are two of the main predictors of cardiovascular disease (CVD). We evaluated whether brachial-ankle pulse wave velocity (baPWV) and common carotid artery intima-media wall thickness (CCA-IMT) are correlated with alcohol consumption in a cross-sectional study among Korean men and women aged 40 years and over. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Federation AMER SOC EXP BIOL | en_US |
dc.subject | Alcohol | en_US |
dc.subject | Carotid intima-media thickness | en_US |
dc.subject | Mediator | en_US |
dc.subject | Pulse wave velocity | en_US |
dc.subject | Subclinical atherosclerosis | en_US |
dc.title | Harmful Relationship between Alcohol Consumption and Brachial Ankle Pulse Wave Velocity : No Favorable Zone for Vascular Damages | en_US |
dc.type | Article | en_US |
dc.relation.volume | 27 | - |
dc.identifier.doi | 10.1016/j.numecd.2014.02.004 | - |
dc.relation.page | 1-1 | - |
dc.relation.journal | FASEB JOURNAL | - |
dc.contributor.googleauthor | Kim, Mi Kyung | - |
dc.contributor.googleauthor | Shin, Jinho | - |
dc.contributor.googleauthor | Choi, Bo Youl | - |
dc.contributor.googleauthor | Kweon, Sun-Seong | - |
dc.contributor.googleauthor | Shin, Dong Hoon | - |
dc.contributor.googleauthor | Lee, Young-Hoon | - |
dc.contributor.googleauthor | Chun, Byung-Yeol | - |
dc.contributor.googleauthor | 김미경 | - |
dc.contributor.googleauthor | 신진호 | - |
dc.contributor.googleauthor | 최보율 | - |
dc.contributor.googleauthor | 권선승 | - |
dc.contributor.googleauthor | 신동훈 | - |
dc.contributor.googleauthor | 이영훈 | - |
dc.contributor.googleauthor | 천병열 | - |
dc.relation.code | 2013009926 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | bychoi | - |
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