Repository at Hanyang UniversityGRADUATE SCHOOL[S](대학원)BIONANOTECHNOLOGY(바이오나노학과)Articles
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dc.contributor.author이영복-
dc.date.accessioned2018-03-26T05:51:45Z-
dc.date.available2018-03-26T05:51:45Z-
dc.date.issued2014-09-
dc.identifier.citationChemical communications, 2014, 50(86), P.13030-13033en_US
dc.identifier.issn1359-7345-
dc.identifier.issn1364-548X-
dc.identifier.urihttp://pubs.rsc.org/en/content/articlelanding/2014/cc/c4cc06199c#!divAbstract-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/52400-
dc.description.abstractHere we present a novel hyperpolarization method, Chemical Reaction-Induced Multi-molecular Polarization (CRIMP), which could be applied to the study of several in vivo processes simultaneously including glycolysis, TCA cycle, fatty acid synthesis and pH mapping. Through the use of non-enzymatic decarboxylation, we generate four hyperpolarized imaging agents from hyperpolarized 1,2- 13 C pyruvic acid. Graphic Abstract Here we present a novel hyperpolarization method, Chemical Reaction-Induced Multi-molecular Polarization (CRIMP), which could be applied to the study of several in vivo processes simultaneously including glycolysis, TCA cycle, fatty acid synthesis and pH mapping.en_US
dc.description.sponsorshipMD Anderson Cancer Center Odyssey Postdoctoral Fellowship (YL), DOD CDMRP PC110065 (NZM), MDACC Institutional Research Grants (PB and NZM), MDACC Institutional Startup (PB), 5 P50 CA 094056-14 (PB), U54 CA151668 (PB), Leukemia and Brain SPORE Developmental Research Awards (PB) and NCI Cancer Center Support Grant CA016672.en_US
dc.language.isoenen_US
dc.publisherRoyal Society of Chemistryen_US
dc.subjectpyruvic aciden_US
dc.subjectacetic acid derivativeen_US
dc.subjectcarbonen_US
dc.subjectfatty aciden_US
dc.subjectArticleen_US
dc.subjectcarbon nuclear magnetic resonanceen_US
dc.subjectchemical reactionen_US
dc.subjectchemical reaction induced multi molecular polarizationen_US
dc.subjectcitric acid cycleen_US
dc.subjectdecarboxylationen_US
dc.subjectdissolutionen_US
dc.subjectfatty acid synthesisen_US
dc.subjecthyperpolarizationen_US
dc.subjectmagnetic fielden_US
dc.subjectnuclear magnetic resonanceen_US
dc.subjectpHen_US
dc.subjectsolid stateen_US
dc.subjectchemistryen_US
dc.subjectglycolysisen_US
dc.subjectnuclear magnetic resonance imagingen_US
dc.subjectnuclear magnetic resonance spectroscopyen_US
dc.subjectsynthesisen_US
dc.titleChemical Reaction-Induced Multi-molecular Polarization (CRIMP)en_US
dc.typeArticleen_US
dc.relation.no86-
dc.relation.volume50-
dc.identifier.doi10.1039/c4cc06199c-
dc.relation.page13030-13033-
dc.relation.journalCHEMICAL COMMUNICATIONS-
dc.contributor.googleauthorLee, Youngbok-
dc.contributor.googleauthorZacharias Millward, Niki M.-
dc.contributor.googleauthorPiwnica-Worms, David-
dc.contributor.googleauthorBhattacharya, Pratip K-
dc.relation.code2014027053-
dc.sector.campusS-
dc.sector.daehakGRADUATE SCHOOL[S]-
dc.sector.departmentDEPARTMENT OF BIONANOTECHNOLOGY-
dc.identifier.pidyblee-
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GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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