Effects of tamsulosin, solifenacin, and combination therapy for the treatment of ureteral stent related discomforts.
- Title
- Effects of tamsulosin, solifenacin, and combination therapy for the treatment of ureteral stent related discomforts.
- Author
- 박성열
- Keywords
- Pain; Stents; Ureter
- Issue Date
- 2011-07
- Publisher
- Korean Urological Association
- Citation
- Investigative and Clinical Urology, 2011, 52(7), P.485-488(4)
- Abstract
- Purpose: To evaluate the effect of tamsulosin, solifenacin, and combination therapy of two agents in improving the lower urinary tract symptoms of patients with indwelling double-J ureteral stents. Materials and Methods: A total of 168 patients underwent placement of a double-J ureteral stent after retrograde ureteroscopy for urinary stone disease. All patients received polyurethane double-J ureteral stents (6 Fr, 24 or 26 cm), which were removed a mean of 14 days postoperatively. A total of 48 patients were given no medication (Group 1), 43 patients were given tamsulosin 0.2 mg once daily (Group 2), 45 patients were given solifenacin 5 mg once daily (Group 3), and 32 patients were given a combination of two agents postoperatively (Group 4). International Prostate Symptom Score/quality of life (IPSS/QoL) and visual analogue pain scale (VAPS) questionnaires were completed by each patient at 1 day postoperatively and on the day of stent removal. Results: In the total group of patients, the mean age was 50.24±12.90 years. There was a significant difference in the IPSS total score between group 1 and groups 3 and 4. Group 4 also differed significantly from group 1 in the irritative subscore. The obstructive subscore differed between groups 2 and 4 and group 1. There was a statistically significant difference between group 1 and group 4 in the QoL score. There were no significant differences in the VAPS. Conclusions: Combination therapy with tamsulosin and solifenacin improved both irritative and obstructive symptoms more than in the other groups. Combination therapy should be strongly considered for patients who complain of stent-related symptoms.
- URI
- https://synapse.koreamed.org/DOIx.php?id=10.4111/kju.2011.52.7.485
- ISSN
- 0494-4747; 2005-6745
- DOI
- 10.4111/kju.2011.52.7.485
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
- Files in This Item:
- kju-52-485.pdfDownload
- Export
- RIS (EndNote)
- XLS (Excel)
- XML