Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 임태연 | - |
dc.date.accessioned | 2018-03-24T02:23:51Z | - |
dc.date.available | 2018-03-24T02:23:51Z | - |
dc.date.issued | 2011-04 | - |
dc.identifier.citation | Biotechnology Letters, 2011, 33(4), P.845-851 | en_US |
dc.identifier.issn | 0141-5492 | - |
dc.identifier.uri | https://link.springer.com/article/10.1007%2Fs10529-010-0492-5 | - |
dc.description.abstract | Fibroblast growth factor 2 (FGF2) stimulates skin wound healing but does long-term delivery of FGF2 enhance skin regeneration compared to short-term delivery? Heparin-conjugated fibrin (HCF) was used as a vehicle for long-term delivery of FGF2. Fibrin, HCF, FGF2-loaded fibrin, and FGF2-loaded HCF were implanted into full-thickness skin defects of mice. The neoepidermis thickness was significantly larger in the FGF2-loaded HCF group than in the other groups, except for the FGF2-loaded fibrin group. Suprabasal cytokeratin differentiation in squamous neoepithelium was greatest in the FGF2-loaded HCF group. The enhanced skin regeneration accompanying the long-term delivery of FGF2 could be mediated, at least partially, by enhanced neovascularization and cell proliferation in the neodermis. | en_US |
dc.description.sponsorship | This work was supported by a grant (A080467) from the Korea Health 21 R&D Project, Ministry of Health, Welfare and Family Affair, Republic of Korea. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer | en_US |
dc.subject | Fibroblast growth factor 2 | en_US |
dc.subject | Heparin-conjugated fibrin | en_US |
dc.subject | Skin regeneration | en_US |
dc.subject | Vascularization | en_US |
dc.title | Skin regeneration with fibroblast growth factor 2 released from heparin-conjugated fibrin | en_US |
dc.type | Article | en_US |
dc.relation.no | 4 | - |
dc.relation.volume | 33 | - |
dc.identifier.doi | 10.1007/s10529-010-0492-5 | - |
dc.relation.page | 845-851 | - |
dc.relation.journal | BIOTECHNOLOGY LETTERS | - |
dc.contributor.googleauthor | Bhang, Suk Ho | - |
dc.contributor.googleauthor | Sun, Ah-Young | - |
dc.contributor.googleauthor | Yang, Hee Seok | - |
dc.contributor.googleauthor | Rhim, Taiyoun | - |
dc.contributor.googleauthor | Kim, Dong-Ik | - |
dc.contributor.googleauthor | Kim, Byung-Soo | - |
dc.relation.code | 2011201360 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF BIOENGINEERING | - |
dc.identifier.pid | rhim | - |
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