Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이현규 | - |
dc.date.accessioned | 2018-03-22T01:11:28Z | - |
dc.date.available | 2018-03-22T01:11:28Z | - |
dc.date.issued | 2016-04 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, v. 85, Page. 9-15 | en_US |
dc.identifier.issn | 0141-8130 | - |
dc.identifier.issn | 1879-0003 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0141813015302324?via%3Dihub | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/50236 | - |
dc.description.abstract | The aim of this study was to improve the solubility of lutein through the use of chitosan (CS)/poly-gamma-glutamic acid (gamma-PGA) nanoencapsulation. In terms of redispersibility, water-soluble chitosan (WsCS)/gamma-PGA nanoparticles (NPs) were better than insoluble chitosan (InCS)/gamma-PGA NPs. The lutein-loaded WsCS/gamma-PGA NP has a spherical form with a size around 200 nm and a narrow size distribution (PDI ˂ 0.1). Solubility measures showed that nanoencapsulation of lutein into WsCS/gamma-PGA NPs resulted in a significant 12-fold higher solubility compared to that of non-nanoencapsulated lutein (p ˂ 0.05). The redispersibility index of the lutein-loaded NPs was 1.01, indicating that they were completely reconstituted into aqueous solution as same as original aqueous solution. These results suggest that WsCS/gamma-PGA nanoencapsulation can be used to enhance the solubility of lutein and other poorly water-soluble compounds. (C) 2015 Elsevier B.V. All rights reserved. | en_US |
dc.description.sponsorship | This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (No. 2014M3A7B4051898). | en_US |
dc.language.iso | en | en_US |
dc.publisher | ELSEVIER SCIENCE BV | en_US |
dc.subject | Lutein | en_US |
dc.subject | Nanoparticle | en_US |
dc.subject | Solubility | en_US |
dc.title | Chitosan/poly-gamma-glutamic acid nanoparticles improve the solubility of lutein | en_US |
dc.type | Article | en_US |
dc.relation.volume | 85 | - |
dc.identifier.doi | 10.1016/j.ijbiomac.2015.12.044 | - |
dc.relation.page | 9-15 | - |
dc.relation.journal | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
dc.contributor.googleauthor | Hong, Da Young | - |
dc.contributor.googleauthor | Lee, Ji-Soo | - |
dc.contributor.googleauthor | Lee, Hyeon Gyu | - |
dc.relation.code | 2016001048 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF HUMAN ECOLOGY[S] | - |
dc.sector.department | DEPARTMENT OF FOOD & NUTRITION | - |
dc.identifier.pid | hyeonlee | - |
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