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Two-View versus Single-View Shear-Wave Elastography: Comparison of Observer Performance in Differentiating Benign from Malignant Breast Masses

Title
Two-View versus Single-View Shear-Wave Elastography: Comparison of Observer Performance in Differentiating Benign from Malignant Breast Masses
Author
구혜령
Keywords
ULTRASOUND ELASTOGRAPHY; MULTIPLE OBSERVERS; LESIONS; US; EXPERIENCE; AGREEMENT; DIAGNOSIS
Issue Date
2014-02
Publisher
RADIOLOGICAL SOC NORTH AMERICA, 820 JORIE BLVD, OAK BROOK, IL 60523 USA
Citation
RADIOLOGY; FEB 2014, 270, 2, p344-p353
Abstract
Purpose: To determine whether two-view shear-wave elastography (SWE) improves the performance of radiologists in differentiating benign from malignant breast masses compared with single-view SWE.Materials and Methods: This prospective study was conducted with institutional review board approval, and written informed consent was obtained. B-mode ultrasonographic (US) and orthogonal SWE images were obtained for 219 breast masses (136 benign and 83 malignant; mean size, 14.8 mm) in 219 consecutive women (mean age, 47.9 years; range, 20-78 years). Five blinded radiologists independently assessed the likelihood of malignancy for three data sets: B-mode US alone, B-mode US and single-view SWE, and B-mode US and two-view SWE. Interobserver agreement regarding Breast Imaging Reporting and Data System (BI-RADS) category and the area under the receiver operating characteristic curve (AUC) of each data set were compared.Results: Interobserver agreement was moderate (k = 0.560 +/- 0.015 [standard error of the mean]) for BI-RADS category assessment with B-mode US alone. When SWE was added to B-mode US, five readers showed substantial interobserver agreement (k = 0.629 +/- 0.017 for single-view SWE; k = 0.651 +/- 0.014 for two-view SWE). The mean AUC of B-mode US was 0.870 (range, 0.855-0.884). The AUC of B-mode US and two-view SWE (average, 0.928; range, 0.904-0.941) was higher than that of B-mode US and single-view SWE (average, 0.900; range, 0.890-0.920), with statistically significant differences for three readers (P <= .003).Conclusion: The performance of radiologists in differentiating benign from malignant breast masses was improved when B-mode US was combined with two-view SWE compared with that when B-mode US was combined with single-view SWE.
URI
http://pubs.rsna.org/doi/abs/10.1148/radiol.13130561http://hdl.handle.net/20.500.11754/49419
ISSN
0033-8419
DOI
10.1148/radiol.13130561
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > ETC
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