Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤태현 | - |
dc.date.accessioned | 2018-03-17T08:44:53Z | - |
dc.date.available | 2018-03-17T08:44:53Z | - |
dc.date.issued | 2012-12 | - |
dc.identifier.citation | Bulletin of the Korean Chemical Society, 33(12), P.4023-4027, 5P. | en_US |
dc.identifier.issn | 1229-5949 | - |
dc.identifier.uri | http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=JCGMCS_2012_v33n12_4023 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/48441 | - |
dc.description.abstract | Cytotoxicity assessment of silver nanoparticles (AgNPs) was performed using MTT-based microfluidic image cytometry (mu FIC). The LC50 value of HeLa cells exposed to AgNPs in the microfluidic device was estimated as 46.7 mg/L, which is similar to that estimated by MTT-based IC for cells cultured in a 96 well plate (49.9 mg/L). These results confirm that the mu FIC approach can produce cytotoxicity data that is reasonably well-matched with that of the conventional 96 well plate system with much higher efficiency. This mu FIC method provides many benefits including ease of use and low cost, and is a more rapid in vitro cell based assay for AgNPs. This may aid in speeding up data acquisition in the field of nanosafety and make a significant contribution to the quantitative understanding of nanoproperty- toxicity relationships. | en_US |
dc.description.sponsorship | This work was financially supported by the Nano R&D program through the Korea Science and Engineering Foundation (KOSEF), which was funded by the Ministry of Education, Science and Technology (MEST) (2008-02968). | en_US |
dc.language.iso | en | en_US |
dc.publisher | 대한화학회 | en_US |
dc.subject | Microfluidic image cytometry | en_US |
dc.subject | Microfluidic device | en_US |
dc.subject | Cytotoxicity assessment | en_US |
dc.subject | Ag nanoparticles | en_US |
dc.subject | Nanotoxicity | en_US |
dc.title | Microfluidic Image Cytometry (mu FIC) Assessments of Silver Nanoparticle Cytotoxicity | en_US |
dc.type | Article | en_US |
dc.relation.no | 12 | - |
dc.relation.volume | 33 | - |
dc.identifier.doi | 10.5012/bkcs.2012.33.12.4023 | - |
dc.relation.page | 4023-4027 | - |
dc.relation.journal | BULLETIN OF THE KOREAN CHEMICAL SOCIETY | - |
dc.contributor.googleauthor | Park, Jonghoon | - |
dc.contributor.googleauthor | Yoon, Tae Hyun | - |
dc.relation.code | 2012214307 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF NATURAL SCIENCES[S] | - |
dc.sector.department | DEPARTMENT OF CHEMISTRY | - |
dc.identifier.pid | taeyoon | - |
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