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dc.contributor.author김진웅-
dc.date.accessioned2018-03-16T02:04:40Z-
dc.date.available2018-03-16T02:04:40Z-
dc.date.issued2014-06-
dc.identifier.citationCOLLOIDS AND SURFACES B-BIOINTERFACES, 권: 116, 페이지: 597-602en_US
dc.identifier.issn0927-7765-
dc.identifier.issn1873-4367-
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S0927776513006620?via%3Dihub-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/47676-
dc.description.abstractCeramide molecules in water-based solutions readily attract each other to form molecular crystals, which seriously hampers to diversify their formulations. This paper describes a facile method that allows fabrication of stable ceramide emulsions through an effective molecular association with a lipid having an asymmetric molecular geometry. The lipid considered in this study is mannosylerythritol lipid (MEL). MEL is specialized in having a unique molecular structure containing sugar alcohol erythritol as a hydrophilic part and two alkyl chains with different number of carbons as hydrophobic moieties. Our particular interest has been focused on experimentally demonstrating how MEL interacts with pseudo-ceramide molecules by observing phase properties, emulsion morphology, and suspension stability. The pseudo-ceramide emulsions prepared with MEL show remarkably improved dispersion stability without either formation of molecular crystals or changes in particle sizes even after storing them for a long time. This suggests that MEL readily associates with the pseudo-ceramide due to the hydrophobic interaction, while it makes a break in the continuity of the molecular assembly of the pseudo-ceramide molecules themselves due to the geometric hindrance coming from MEL's asymmetric molecular structure. (C) 2013 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipThis work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea Government (MSIP) (No. 2008-0061891) and by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2012R1A1A2039). This research was also supported by "Development of Enhanced Oil Recovery Techniques using BT/NT Fusion Technology" project of the Korea Institute of Geoscience and Mineral Resources (KIGAM) funded by the Ministry of Knowledge Economy (MEK) of Korea.en_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSen_US
dc.subjectPseudo-ceramideen_US
dc.subjectCrystalsen_US
dc.subjectEmulsionsen_US
dc.subjectLipiden_US
dc.subjectMolecular geometryen_US
dc.titleNanoemulsification of pseudo-ceramide by molecular association with mannosylerythritol lipiden_US
dc.typeArticleen_US
dc.relation.volume116-
dc.identifier.doi10.1016/j.colsurfb.2013.10.022-
dc.relation.page597-602-
dc.relation.journalCOLLOIDS AND SURFACES B-BIOINTERFACES-
dc.contributor.googleauthorKim, Min-Kyung-
dc.contributor.googleauthorJeong, Eun-Seon-
dc.contributor.googleauthorKim, Kwang-Nyeon-
dc.contributor.googleauthorPark, Seung-Han-
dc.contributor.googleauthorKim, Jin-Woong-
dc.relation.code2014027563-
dc.sector.campusS-
dc.sector.daehakGRADUATE SCHOOL[S]-
dc.sector.departmentDEPARTMENT OF BIONANOTECHNOLOGY-
dc.identifier.pidkjwoong-
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GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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