Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박용수 | - |
dc.date.accessioned | 2018-03-16T01:43:19Z | - |
dc.date.available | 2018-03-16T01:43:19Z | - |
dc.date.issued | 2014-06 | - |
dc.identifier.citation | JOURNAL OF KOREAN MEDICAL SCIENCE , 권: 29 호: 1, p 90-97 | en_US |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.issn | 1598-6357 | - |
dc.identifier.uri | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890482/ | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/47649 | - |
dc.description.abstract | We studied the efficacy and safety of acarbose in comparison with voglibose in type 2 diabetes patients whose blood glucose levels were inadequately controlled with basal insulin alone or in combination with metformin (or a sulfonylurea). This study was a 24-week prospective, open-label, randomized, active-controlled multi-center study. Participants were randomized to receive either acarbose (n= 59, 300 mg/day) or voglibose (n = 62, 0.9 mg/day). The mean HbA(1c) at week 24 was significantly decreased approximately 0.7% from baseline in both acarbose (from 8.43% +/- 0.71% to 7.71% +/- 0.93%) and voglibose groups (from 8.38% +/- 0.73% to 7.68% +/- 0.94%). The mean fasting plasma glucose level and self-monitoring of blood glucose data from 1 hr before and after each meal were significantly decreased at week 24 in comparison to baseline in both groups. The levels 1 hr after dinner at week 24 were significantly decreased in the acarbose group (from 233.54 +/- 69.38 to 176.80 +/- 46.63 mg/dL) compared with the voglibose group (from 224.18 +/- 70.07 to 193.01 +/- 55.39 mg/dL). In conclusion, both acarbose and voglibose are efficacious and safe in patients with type 2 diabetes who are inadequately controlled with basal insulin. | en_US |
dc.description.sponsorship | The work was funded by a research grant from the Bayer Korea Ltd 2009.09.22-2012.09.18). | en_US |
dc.language.iso | en | en_US |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES, 302 75 DONG DU ICHON, DONG YONGSAN KU, SEOUL 140 031, SOUTH KOREA | en_US |
dc.subject | Diabetes Mellitus, Type 2 | en_US |
dc.subject | Acarbose | en_US |
dc.subject | Voglibose | en_US |
dc.title | Comparison of Acarbose and Voglibose in Diabetes Patients Who Are Inadequately Controlled with Basal Insulin Treatment: Randomized, Parallel, Open-Label, Active-Controlled Study | en_US |
dc.type | Article | en_US |
dc.relation.no | 1 | - |
dc.relation.volume | 29 | - |
dc.identifier.doi | 10.3346/jkms.2014.29.1.90 | - |
dc.relation.page | 90-97 | - |
dc.relation.journal | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.contributor.googleauthor | Lee, Mi Young | - |
dc.contributor.googleauthor | Choi, Dong Seop | - |
dc.contributor.googleauthor | Lee, Moon Kyu | - |
dc.contributor.googleauthor | Lee, Hyoung Woo | - |
dc.contributor.googleauthor | Park, Tae Sun | - |
dc.contributor.googleauthor | Kim, Doo Man | - |
dc.contributor.googleauthor | Chung, Choon Hee | - |
dc.contributor.googleauthor | Kim, Duk Kyu | - |
dc.contributor.googleauthor | Kim, In Joo | - |
dc.contributor.googleauthor | Park, Yong Soo | - |
dc.relation.code | 2014033608 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | parkys | - |
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