Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 염종훈 | - |
dc.date.accessioned | 2018-03-16T01:29:19Z | - |
dc.date.available | 2018-03-16T01:29:19Z | - |
dc.date.issued | 2014-06 | - |
dc.identifier.citation | Korean Journal of Anesthesiology, 권: 66 호: 6, p 439-443 | en_US |
dc.identifier.issn | 2005-6419 | - |
dc.identifier.uri | https://ekja.org/journal/view.php?doi=10.4097/kjae.2014.66.6.439 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/47626 | - |
dc.description.abstract | Background: In this study, we assessed the 50% effective concentration (EC50) of sevoflurane for reducing a rocuronium-induced reaction, based on the Dixon’s up-and-down method. We also assessed the 50 and 95% effective end-tidal concentration of sevoflurane (ETsev), based on the probit regression curve of the probability of nonwithdrawal reaction.Methods: We conducted a prospective, double-blind study in 23 males and 24 females. After using 2.5% thiopental sodium (4 mg/kg), anesthesia was induced in the patients. The patients then inhaled sevoflurane with 5 vol% in 6 L/min of oxygen. When the target ETsev was achieved, a nurse injected the intubating dose of rocuronium (0.6 mg/kg) for 5-10 s under the free flow of intravenous fluid. After the nurse evaluated the response, the nurse recorded the maximum heart rate during 30 s and the mean arterial pressure after rocuronium injection.Results: Based on Dixon’s up-and-down method, the EC50 of sevoflurane was 2.5 ± 0.5 vol% in males and 2.5 ± 0.3 vol% in females. The probit regression curve of the probability of nonwithdrawal reaction showed that in males the 50% effective ETsev was 2.4 vol% (95% confidence interval [CI], 1.5-3.1 vol%) and the 95% effective ETsev was 3.5 vol% (95% CI, 2.9-11.0 vol%); in females, the 50% effective ETsev was 2.4 vol% (95% CI, 2.1-2.7 vol%) and the 95% effective ETsev was 3.0 vol% (95% CI, 2.7-4.5 vol%).Conclusions: The inhalation of sevoflurane during the induction period may provide a simple and reliable means of reducing rocuronium-induced reactions without adverse hemodynamic changes. There was no significant difference between males and females. | en_US |
dc.language.iso | other | en_US |
dc.publisher | Korean Society Of Anesthesiologists | en_US |
dc.subject | Rocuronium | en_US |
dc.subject | Sevoflurane | en_US |
dc.subject | Withdrawal | en_US |
dc.title | End-tidal concentration of sevoflurane for reducing rocuronium-induced withdrawal reactions in adult patients: A comparison between male and female patients | en_US |
dc.type | Article | en_US |
dc.relation.no | 6 | - |
dc.relation.volume | 66 | - |
dc.identifier.doi | 10.4097/kjae.2014.66.6.439 | - |
dc.relation.page | 439-443 | - |
dc.relation.journal | Korean Journal of Anesthesiology | - |
dc.contributor.googleauthor | Yeom, Jong Hoon | - |
dc.contributor.googleauthor | Kim, Kyoung Hun | - |
dc.contributor.googleauthor | Choe, Gyu Ho | - |
dc.contributor.googleauthor | Lee, Jae Min | - |
dc.relation.code | 2014015879 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | yeomjh | - |
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