A case of chronic myeloid leukemia with features of essential thrombocythemia in peripheral blood and bone marrow
- Title
- A case of chronic myeloid leukemia with features of essential thrombocythemia in peripheral blood and bone marrow
- Author
- 박병배
- Keywords
- Chronic myeloid leukemia; Philadelphia chromosome; Essential thrombocythemia
- Issue Date
- 2014-06
- Publisher
- 대한혈액학회
- Citation
- Blood Research, 권: 49, 호: 2, 페이지: 127-129
- Abstract
- Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by over-production of myeloid white blood cells. Philadelphia chromosome is an essential finding for CML diagnosis. Generally, a clinical diagnosis of essential thrombocythemia (ET) can be established from isolated marked thrombocytosis in peripheral blood. However, Philadelphia chromosome-positivity or bcr/abl rearrangement with isolated thrombocy-tosis should be diagnosed as CML, not ET, according to World Health Organization diag-nostic criteria. Therefore, CML should not be excluded before confirming the presence of the Philadelphia chromosome or bcr/abl rearrangement in cases of isolated thrombocy-tosis in peripheral blood. We report a case of CML with clinical features of ET in a patient successfully treated with imatinib.
- URI
- https://www.synapse.koreamed.org/search.php?where=aview&id=10.5045/br.2014.49.2.127&code=3072BR&vmode=FULLhttp://hdl.handle.net/20.500.11754/47329
- ISSN
- 2287-979X
- DOI
- 10.5045/br.2014.49.2.127
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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