Fiber-optic raster scanning two-photon endomicroscope using a tubular piezoelectric actuator
- Title
- Fiber-optic raster scanning two-photon endomicroscope using a tubular piezoelectric actuator
- Author
- 유홍기
- Keywords
- two-photon microscopy; endomicroscopy; fiber scanning; raster scanning; tubular piezoelectric actuator; endoscopic imaging
- Issue Date
- 2014-06
- Publisher
- SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS, 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98225 USA
- Citation
- JOURNAL OF BIOMEDICAL OPTICS, 권: 19, 호: 6
- Abstract
- A nonresonant, fiber-optic raster scanning endomicroscope was developed using a quarter-tubular piezoelectric (PZT) actuator. A fiber lever mechanism was utilized to enhance the small actuation range of the tubular PZT actuator and to increase its field-of-view. Finite element method simulation of the endoscopic probe was conducted for various conditions to maximize its scanning range. After fabricating the probe using a double clad fiber, we obtained two-photon fluorescence images using raster beam scanning of the fiber. The outer diameter of the probe was 3.5 mm and its rigid distal length was 30 mm including a high numerical aperture gradient index lens. These features are sufficient for input into the instrumental channel of a commercial colonoscope or gastroscope to obtain high resolution images in vivo. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
- URI
- https://www.spiedigitallibrary.org/journals/Journal-of-Biomedical-Optics/volume-19/issue-6/066010/Fiber-optic-raster-scanning-two-photon-endomicroscope-using-a-tubular/10.1117/1.JBO.19.6.066010.full?SSO=1http://hdl.handle.net/20.500.11754/47219
- ISSN
- 1083-3668; 1560-2281
- DOI
- 10.1117/1.JBO.19.6.066010
- Appears in Collections:
- COLLEGE OF ENGINEERING[S](공과대학) > ELECTRICAL AND BIOMEDICAL ENGINEERING(전기·생체공학부) > Articles
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