Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이원무 | - |
dc.date.accessioned | 2018-03-15T02:10:16Z | - |
dc.date.available | 2018-03-15T02:10:16Z | - |
dc.date.issued | 2012-04 | - |
dc.identifier.citation | European Journal of Obstetrics & Gynecology and Reproductive Biology, 2012, 161(2), P.219-223 | en_US |
dc.identifier.issn | 0301-2115 | - |
dc.identifier.uri | http://www.ejog.org/article/S0301-2115(12)00007-3/fulltext | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/46988 | - |
dc.description.abstract | Objective: Locally advanced bulky cervical cancer (LABCC) is characterized by poor local control. The objective of this study was to identify the clinicopathologic variables associated with one-year central-only recurrence, which will serve as criteria for adjuvant hysterectomy after radiation (AHR) in patients with LABCC. Study design: Between January 2000 and August 2007, we retrospectively evaluated outcomes in 225 patients with LABCC who were initially treated with radiation or chemoradiation. Results: Among the 225 patients with LABCC, there were 41 recurrences within one year after treatment (8 central-only and 33 pelvis and/or distant site recurrences). Age, stage, and treatment type were not associated with the one-year central-only recurrences, but tumor size >= 8 cm had a statistically significant association based on multivariate analysis (OR, 5.39; 95% CI, 1.15-25.31; p = 0.03). The combination of non-squamous cell (non-SCC) type and tumor size >= 8 cm had a significantly higher rate of recurrence within one year (OR, 43.0; 95% CI, 4.78-386.68; p < 0.01). Conclusions: Of patients with LABCC, those with non-SCC tumors >= 8 cm in size were at high risk for early central-only recurrence after cisplatin-based chemoradiation, and represent the subset of patients for whom AHR is beneficial. (C) 2012 Elsevier Ireland Ltd. All rights reserved. | en_US |
dc.description.sponsorship | Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Science B.V., Amsterdam. | en_US |
dc.subject | Uterine cervical neoplasm | en_US |
dc.subject | Recurrence | en_US |
dc.subject | Local neoplasm recurrence | en_US |
dc.subject | Adjuvant hysterectomy | en_US |
dc.title | Clinicopathologic factors for central recurrence in patients with locally advanced bulky cervical cancer | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1016/j.ejogrb.2011.12.029 | - |
dc.relation.journal | EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY | - |
dc.contributor.googleauthor | Lee, Won-Moo | - |
dc.contributor.googleauthor | Park, Sang-Il | - |
dc.contributor.googleauthor | Kim, Beob-Jong | - |
dc.contributor.googleauthor | Kim, Moon-Hong | - |
dc.contributor.googleauthor | Choi, Seok-Cheol | - |
dc.contributor.googleauthor | Lee, Eui-Don | - |
dc.contributor.googleauthor | Ryu, Sang-Young | - |
dc.relation.code | 2012219298 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | leewmoo | - |
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