Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 한동수 | - |
dc.date.accessioned | 2018-03-14T08:13:23Z | - |
dc.date.available | 2018-03-14T08:13:23Z | - |
dc.date.issued | 2014-07 | - |
dc.identifier.citation | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY; JUN 2014, 29, 6, p1223-p1228 | en_US |
dc.identifier.issn | 0815-9319 | - |
dc.identifier.uri | http://onlinelibrary.wiley.com/doi/10.1111/jgh.12521/full | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/46806 | - |
dc.description.abstract | Background and AimPrior studies have reported 2-L polyethylene glycol (PEG) plus ascorbic acid (PEG+Asc) is an effective alternative to standard 4-L PEG for bowel preparation before colonoscopy, but they are limited because of some confounders. Therefore, we compared the efficacy, patient compliance, satisfaction, and safety of 2-L PEG+Asc versus 4-L PEG for bowel cleansing in optimal preparation strategies.MethodsIn this prospective, randomized, single-blind trial, consenting outpatients were randomly assigned to one of two arms. All colonoscopies were scheduled in the morning and cleansing solutions were administered as a split-dose regimen. Bowel-cleansing efficacy in three different segments was measured on a five-point scale with four-point overall grading. Patients' opinions of the preparation regimens were obtained by questionnaire.ResultsThere was no significant difference between the 2-L PEG+Asc (159/163; 97.5%) and 4-L PEG (162/164; 98.8%) with respect to the overall success of bowel cleansing (mean difference=-1.3 [-4.1-]). Patient compliance, acceptability, and satisfaction were better in the 2-L PEG+Asc arm than the 4-L PEG arm (P<0.05). Additionally, the incidence of side effects was lower in the 2-L PEG+Asc than the 4-L PEG (overall, 57.7% vs 73.2%, P<0.05). However, no significant difference was seen in patients' rating of taste.ConclusionsIn an optimal preparation setting, 2-L PEG+Asc has equal efficacy as a bowel cleanser prior to colonoscopy as 4-L PEG, with the advantages of better patient compliance, satisfaction, and safety. | en_US |
dc.language.iso | en | en_US |
dc.publisher | WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA | en_US |
dc.subject | ascorbic acid | en_US |
dc.subject | bowel preparation | en_US |
dc.subject | colonoscopy | en_US |
dc.subject | polyethylene glycol | en_US |
dc.title | Randomized trial of 2-L polyethylene glycol plus ascorbic acid versus 4-L polyethylene glycol as bowel cleansing for colonoscopy in an optimal setting | en_US |
dc.type | Article | en_US |
dc.relation.volume | 29 | - |
dc.identifier.doi | 10.1111/jgh.12521 | - |
dc.relation.page | 1223-1228 | - |
dc.relation.journal | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.contributor.googleauthor | Moon, Chang Mo | - |
dc.contributor.googleauthor | Park, Dong Il | - |
dc.contributor.googleauthor | Choe, Young Ghil | - |
dc.contributor.googleauthor | Yang, Dong-Hoon | - |
dc.contributor.googleauthor | Yu, Yeon Hwa | - |
dc.contributor.googleauthor | Eun, Chang Soo | - |
dc.contributor.googleauthor | Han, Dong Soo | - |
dc.relation.code | 2014033286 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | hands | - |
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