Toxicology study with microRNA
- Title
- Toxicology study with microRNA
- Author
- 황승용
- Keywords
- microRNA; miRNA; Toxicology; Toxicoepigenomics; Epigenomics
- Issue Date
- 2014-06
- Publisher
- KOREAN SOCIETY TOXICOGENOMICS & TOXICOPROTEOMICS-KSTT, HANYANG UNIV, SCI & TECHNOL BLDG 1, RM 423, SA-DONG, SANGROK-GU, ANSAN, GYEONGGI-DO, 426 791, SOUTH KOREA
- Citation
- MOLECULAR & CELLULAR TOXICOLOGY, 권: 10, 호: 2, 페이지: 127-134
- Abstract
- microRNAs have a principal role in many biological processes, such as gene expression, control and development, as well as cellular processes. In recent years, microRNAs have attracted great interest in the field of toxicology. When organisms are exposed to toxic compounds, microRNAs expression is altered, which affects mRNA transcription and protein translation and causes adverse biological effects. Here, we introduce microRNAs as research tools, the specific expression profile of microRNAs following exposure to different toxicants or diseases that were found to be sensitive biomarkers. Finally, we address several issues related to microRNAs in toxicological studies.
- URI
- http://link.springer.com/article/10.1007%2Fs13273-014-0014-yhttp://hdl.handle.net/20.500.11754/46577
- ISSN
- 1738-642X; 2092-8467
- Appears in Collections:
- GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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