Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김지은 | - |
dc.date.accessioned | 2018-03-14T04:26:26Z | - |
dc.date.available | 2018-03-14T04:26:26Z | - |
dc.date.issued | 2013-06 | - |
dc.identifier.citation | INFECTION, JUN 2013, 41(3), p603-p612 | en_US |
dc.identifier.issn | 0300-8126 | - |
dc.identifier.uri | https://link.springer.com/article/10.1007/s15010-013-0441-z | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/46565 | - |
dc.description.abstract | The aim of this study was to determine the risk factors and clinical characteristics of community-acquired acute pyelonephritis (CA-APN) caused by extended-spectrum beta-lactamase (ESBL)-producing organisms.From March 2010 to February 2011, patients with CA-APN were recruited in 11 hospitals in South Korea. Clinical and microbiological data were collected prospectively, and the ESBLs and multilocus sequence types of the ESBL-producing Escherichia coli were characterized. Comparison between CA-APN caused by ESBL-producing Enterobacteriaceae and those by non-ESBL-producing organisms was performed.A total of 566 patients were recruited. Enterobacteriaceae were detected in 526 patients. Forty-six isolates (46/526, 8.7 %) were positive for ESBLs. Clinical and microbiological failure did not differ between the two groups, despite there being fewer patients with ESBL-positive isolates provided with appropriate antibiotics initially (19.6 vs. 93.8 %, p < 0.001). However, the duration of hospitalization was longer in the ESBL group (10.5 vs. 7.0 days, p = 0.012). In a logistic regression model, Charlson score a parts per thousand yen1 point [odds ratio (OR) 3.4, 95 % confidence interval (CI) 1.6-7.0, p = 0.001], antibiotics usage during the previous year (OR 3.1, 95 % CI 1.4-7.2, p = 0.008), and urinary catheterization during the previous month (OR 4.4, 95 % CI 1.1-17.6, p = 0.035) were associated with the risks of CA-APN by ESBL producers. CTX-M-15 (48 %) and CTX-M-14 (38 %) were the most common ESBLs. ST131 was the most common clone (7/24, 29.1 %), which was more frequently resistant to cefepime, fosfomycin, and temocillin.The risk factors for CA-APN by ESBL producers were Charlson score a parts per thousand yen1 point, antibiotics usage during the previous year, and urinary catheterization during the previous month. | en_US |
dc.description.sponsorship | This work was supported by a grant from the Korea Healthcare Technology R&D Project, Ministry of Health & Welfare, Republic of Korea. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer Science + Business Media | en_US |
dc.subject | Extended-spectrum beta-lactamase | en_US |
dc.subject | Urinary tract infection | en_US |
dc.subject | Community acquired | en_US |
dc.subject | Risk factor | en_US |
dc.title | Clinical characteristics of community-acquired acute pyelonephritis caused by ESBL-producing pathogens in South Korea | en_US |
dc.type | Article | en_US |
dc.relation.no | 3 | - |
dc.relation.volume | 41 | - |
dc.identifier.doi | 10.1007/s15010-013-0441-z | - |
dc.relation.page | 603-612 | - |
dc.relation.journal | INFECTION | - |
dc.contributor.googleauthor | Kim, B. | - |
dc.contributor.googleauthor | Kim, J. | - |
dc.contributor.googleauthor | Seo, M. R. | - |
dc.contributor.googleauthor | Wie, S. H. | - |
dc.contributor.googleauthor | Cho, Y. K. | - |
dc.contributor.googleauthor | Lim, S. K. | - |
dc.contributor.googleauthor | Lee, J. S. | - |
dc.contributor.googleauthor | Kwon, K. T. | - |
dc.contributor.googleauthor | Lee, H. | - |
dc.contributor.googleauthor | Cheong, H. J. | - |
dc.relation.code | 2013010252 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | quidam76 | - |
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